Validating Minimally Invasive Laser Doppler Flowmetry for Serial Bone Perfusion Measurements in Mice

NJ Hanne, ED Easter, JH Cole - BioRxiv, 2019 - biorxiv.org
In vivo laser Doppler flowmetry (LDF) has previously been used to quantify blood perfusion
accurately at a single timepoint in the murine tibial metaphysis. However, this procedure …

[图书][B] Characterizing Osteovascular Structure and Function with High Fat Diet-Induced Obesity and Stroke

NJ Hanne - 2019 - search.proquest.com
Functional vasculature is essential for maintaining skeletal integrity and preventing fracture.
Microvessels within bone not only supply oxygen and nutrients directly to sites of active …

[PDF][PDF] Repeated laser doppler flowmetry procedures in bone do not alter perfusion, localized inflammation, or gait patterns

E Easter - 2017 - repository.lib.ncsu.edu
Bone is a highly vascularized tissue that requires adequate blood perfusion to remodel in
response to loading and heal after fracturing. Laser Doppler flowmetry (LDF) is a technique …