Chalcones and their derivatives have been widely studied due to their versatile
pharmacological and biological activities, such as anti-inflammatory, antibacterial, antiviral …

Endometriosis is a gynecological disorder among reproductive-aged women. Recent
epidemiological investigations suggest endometriosis increases the risk of endometrial …

The emergence of the COVID-19 situation has become a global issue due to the lack of
effective antiviral drugs for treatment. Flavonoids are a class of plant secondary metabolites …

The interleukin (IL)-1 family is a major proinflammatory cytokine family, ranging from the well-
studied IL-1s to the most recently discovered IL-33. As a new focus, IL-33 has attracted …

African swine fever (ASF) causes high mortality in pigs and threatens global swine
production. There is still a lack of therapeutics available, with two vaccines under scrutiny …

Background: Over-expression of Vascular Endothelial Growth Factor Receptors (VEGFRs)
leads to the hyperactivation of oncogenes. For inhibition of this hyperactivation, the USA …

Background Human nucleotide triphosphate diphosphatase (NUDT15) is one of the
essential proteins involved in the hydrolysis of anti-cancer drugs against leukemia …

In this study, five 3-aryloxirane-2-carboxylate derivatives were prepared, and the
antiproliferative activities of molecules were screened in lung and colon cancer cell lines …

This study aims to evaluate the antitrypanosomiasis activity of a synthetic dichloro-
substituted aminochalcone via in vitro assays against infected cell cultures, as well as a …

Background: Porcine epidemic diarrhea virus (PEDV) is a recurring coronavirus that causes
severe diarrhea in pigs with high mortality and morbidity rates, especially in neonatal pigs …