From protein film electrochemistry to nanoconfined enzyme cascades and the electrochemical leaf
Protein film electrochemistry (PFE) has given unrivalled insight into the properties of redox
proteins and many electron-transferring enzymes, allowing investigations of otherwise ill …
proteins and many electron-transferring enzymes, allowing investigations of otherwise ill …
Deciphering Photoinduced Catalytic Reaction Mechanisms in Natural and Artificial Photosynthetic Systems on Multiple Temporal and Spatial Scales Using X-ray …
Utilization of renewable energies for catalytically generating value-added chemicals is
highly desirable in this era of rising energy demands and climate change impacts. Artificial …
highly desirable in this era of rising energy demands and climate change impacts. Artificial …
NADP (H)-dependent biocatalysis without adding NADP (H)
RA Herold, R Reinbold, CJ Schofield… - Proceedings of the …, 2023 - National Acad Sciences
Isocitrate dehydrogenase 1 (IDH1) naturally copurifies and crystallizes in a resting state with
a molecule of its exchangeable cofactor, NADP+/NADPH, bound in each monomer of the …
a molecule of its exchangeable cofactor, NADP+/NADPH, bound in each monomer of the …
Electrochemical Nanoreactor Provides a Comprehensive View of Isocitrate Dehydrogenase Cancer‐drug Kinetics
RA Herold, CJ Schofield, FA Armstrong - Angewandte Chemie, 2023 - Wiley Online Library
The ability to control enzyme cascades entrapped in a nanoporous electrode material (the
“Electrochemical Leaf”, e‐Leaf) has been exploited to gain detailed kinetic insight into the …
“Electrochemical Leaf”, e‐Leaf) has been exploited to gain detailed kinetic insight into the …
Exploiting electrode nanoconfinement to investigate the catalytic properties of isocitrate dehydrogenase (IDH1) and a cancer-associated variant
RA Herold, R Reinbold, CF Megarity… - The Journal of …, 2021 - ACS Publications
Human isocitrate dehydrogenase (IDH1) and its cancer-associated variant (IDH1 R132H)
are rendered electroactive through coconfinement with a rapid NADP (H) recycling enzyme …
are rendered electroactive through coconfinement with a rapid NADP (H) recycling enzyme …
Highly Efficient and Selective Visible‐light Photocatalytic CO2 Reduction to CO Using a 2D Co(II)‐Imidazole MOF as Cocatalyst and Ru(bpy)3Cl2 as Photosensitizer
L Wang, H Zhang, Z Zhang, J Zhang… - Chemistry–An Asian …, 2023 - Wiley Online Library
The first application of an imidazole MOF, the 2D Co (II)‐imidazole framework,{[Co (TIB) 2
(H2O) 4] SO4}(TIB stands for 1, 3, 5‐tris (1‐imidazolyl) benzene)(CoTIB) in photocatalytic …
(H2O) 4] SO4}(TIB stands for 1, 3, 5‐tris (1‐imidazolyl) benzene)(CoTIB) in photocatalytic …
Interactive biocatalysis achieved by driving enzyme cascades inside a porous conducting material
An emerging concept and platform, the electrochemical Leaf (e-Leaf), offers a radical
change in the way tandem (multi-step) catalysis by enzyme cascades is studied and …
change in the way tandem (multi-step) catalysis by enzyme cascades is studied and …
[HTML][HTML] 65 years of electron transfer
CP Hsu, L Hammarström, MD Newton - The Journal of Chemical …, 2022 - pubs.aip.org
Electron transfer (ET), as a simplest chemical reaction, is the fundamental step in the
oxidation–reduction reaction, involved in a large class of electrochemistry, biochemistry, and …
oxidation–reduction reaction, involved in a large class of electrochemistry, biochemistry, and …
[HTML][HTML] Metabolic engineering on a 3D-printed microfluidic platform: A new approach for modular co-metabolic pathways
SH Helalat, I Seder, RC Téllez, M Amani… - Chemical Engineering …, 2024 - Elsevier
Metabolic engineering of cell factories often requires extensive modification of host cellular
machinery, leading to numerous challenges such as metabolic burden, intermediate …
machinery, leading to numerous challenges such as metabolic burden, intermediate …
Novel Cytochrome P450-3A4 Enzymatic Nanobiosensor for Lapatinib (a Breast Cancer Drug) Developed on a Poly (anilino-co-4-aminobenzoic Acid-Green …
JL January, ZZ Tshobeni, NPP Ngema, AN Jijana… - Biosensors, 2023 - mdpi.com
Breast cancer (BC) is one of the most common types of cancer disease worldwide and it
accounts for thousands of deaths annually. Lapatinib is among the preferred drugs for the …
accounts for thousands of deaths annually. Lapatinib is among the preferred drugs for the …