Anaemia is a global public health problem affecting both developing and developed
countries with major consequences for human health as well as social and economic …

Background: Blood transfusion is a traditional treatment for β-thalassemia (β-thal) that
improves the patients' anemia and lifespan, but it may lead to iron overload in parenchymal …

Patients with β-thalassemia require lifelong iron chelation therapy from early childhood to
prevent complications associated with transfusional iron overload. To evaluate long-term …

Background. Endocrinopathies are common in patients with β‐thalassemia major despite
parenteral iron chelation therapy with deferoxamine. Prevalence of abnormal glucose …

Background Beta thalassemia major (TM) is the most common inherited genetic disorder
worldwide. Patients are at risk of iron overload, which leads to various forms of tissue …

Introduction: Iron overload is a major problem in patients with b-thalassemia major, and it
has many structural and metabolic consequences. In this study, we aimed to consider the …

Objectives: The aim of this study was to determine the anthropometric measurements in
transfusion-dependent β-thalassemia children in Pakistan. The secondary aim was to …

Results: A total of 48 patients (22 males and 26 females) completed a 12 year-period of
follow-up. During this period, hypothyroidism was diagnosed in 17/48 (35%) of patients …

Purpose Transfusion-dependent beta-thalassemia (TDT) patients suffer from various
endocrinopathies. The main contributing factor associated with these complications is iron …

Background: Endocrinopathies are common in patients with thalassaemia major (TM)
despite parenteral iron chelation therapy with deferoxamine. There are only a few studies on …