Reactive oxygen species (ROS) are fundamental for macrophages to eliminate invasive
microorganisms. However, as observed in nonphagocytic cells, ROS play essential roles in …

Macrophages are the most abundant immune cells within the synovial joints, and also the
main innate immune effector cells triggering the initial inflammatory responses in the …

Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial
infarction, but morbidity and mortality of acute myocardial infarction are still high …

Recent studies have established a strong link between copper and cancer biology, as
copper is necessary for cancer growth and metastasis. Beyond the conventional concept of …

Ulcerative colitis (UC), as a most common inflammatory bowel disease (IBD), has become a
global public health concern. Exploring novel method of treating UC is urgent and …

Superoxide dismutase (SOD) is a class of enzymes that restrict the biological oxidant cluster
enzyme system in the body, which can effectively respond to cellular oxidative stress, lipid …

The roots of Salvia miltiorrhiza have been used in Traditional Chinese Medicine for
thousands of years. However, tons of aerial parts of this plant are usually discarded in the …

Advances in synthetic biology and the clinical application of bacteriotherapy enable the use
of genetically engineered bacteria (GEB) to combat various diseases. GEB act as a small …

Purpose Lipopolysaccharide (LPS) pretreatment can enhance the therapeutic effect of
dental follicle stem cells-derived small extracellular vesicles (DFC-sEV) for periodontitis, and …

Genetically engineered bacteria (GEB) have shown significant promises to revolutionize
modern medicine. These engineered bacteria with unique properties such as enhanced …