Cancer is one of the greatest public health challenges. According to the World Health
Organization (WHO), 9.6 million cancer deaths have been reported in 2018. The most …

Vitamin D shows a variety of pleiotropic activities which cannot be fully explained by the
stimulation of classic pathway-and vitamin D receptor (VDR)-dependent transcriptional …

Pirfenidone (PFN) is an anti-fibrotic drug with significant anti-inflammatory property used for
treatment of fibrotic conditions such as idiopathic pulmonary fibrosis (IPF). In the coronavirus …

The genomic actions of the vitamin D are mediated via its biologically most potent metabolite
1α, 25‐dihydroxyvitamin D3 (1, 25 (OH) 2D3) and the transcription factor vitamin D receptor …

A role for vitamin D in immune modulation and in cancer has been suggested. In this work,
we report that mice with increased availability of vitamin D display greater immune …

Vitamin D is the sunshine vitamin. During exposure to sunlight, 7-dehydrocholesterol in the
skin absorbs ultraviolet B (UVB) radiation converting it to previtamin D3. Previtamin D3 …

Prostate cancer (PrCa) is the second most common cancer worldwide in males. While
strongly warranted, the prediction of mortality risk due to PrCa, especially before its …

Classically, a secosteroid hormone, vitamin D, has been implicated in calcium and
phosphate homeostasis and has been associated with the pathogenesis of rickets and …

Despite recent advances in treatment, overall survival rates for metastatic melanoma,
especially those that invade the lungs, continue to be low, with 5-year survival rates of only …

Objective This study examined the effects of miR‐122–enriched exosomes on the
expression of vitamin D3 receptor (VDR) and sterol regulatory element‐binding transcription …