Is interleukin-10 gene polymorphism a predictive marker in HCV infection?

BJ Świątek - Cytokine & growth factor reviews, 2012 - Elsevier
The clinical outcome of hepatitis C virus (HCV) infection varies between individuals–from
spontaneous viral clearance and persistence without complication, to chronic hepatitis …

[HTML][HTML] Polymorphisms of some cytokines and chronic hepatitis B and C virus infection

QJ Gao, DW Liu, SY Zhang, M Jia… - World journal of …, 2009 - ncbi.nlm.nih.gov
AIM: To study the relationship between the polymorphisms in some cytokines and the
outcome of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection. METHODS …

Polymorphisms in the interleukin-10, tumor necrosis factor-α, and transforming growth factor-β1 genes in chronic hepatitis C patients treated with interferon and …

PG Vidigal, JJ Germer, NN Zein - Journal of hepatology, 2002 - Elsevier
Background/Aims: In hepatitis C infection, the production of inappropriate cytokine levels
appears to contribute to viral persistence and to affect the response to antiviral therapy …

[PDF][PDF] Interferon-gamma: biologic functions and HCV therapy (type I/II)

A Gattoni, A Parlato, B Vangieri, M Bresciani, R Derna - Clin Ter, 2006 - clinicaterapeutica.it
Abstract Purpose. To discuss exhaustively: 1) the interferon-gamma in inducing and
modulating of immune responses; 2) impairment of IFN-γ production that plays an important …

Frequency of the HIV-protective CC chemokine receptor 5-Δ32/Δ32 genotype is increased in hepatitis C

RP Woitas, G Ahlenstiel, A Iwan, JK Rockstroh… - Gastroenterology, 2002 - Elsevier
Background & Aims: A homozygous 32–base pair deletion in the CCR5 gene (CCR5-Δ32)
protects against human immunodeficiency virus infection (HIV). However, the role of this …

Different cytokine profiles of peripheral blood mononuclear cells from patients with persistent and self-limited hepatitis C virus infection

M Sarih, N Bouchrit, A Benslimane - Immunology letters, 2000 - Elsevier
An imbalance between T helper cell Th1 and Th2 like cytokines has been described in
several chronic infectious diseases. In an attempt to characterise the mechanism …

[PDF][PDF] Serum profile of T helper 1 and T helper 2 cytokines in patients with chronic hepatitis C virus infection

B Abayli, A Canataroglu… - Turkish Journal of …, 2003 - turkjgastroenterol.org
Background! aims: T cell immunoregulatory cytokines may play a crucial role in the host
response to hepatitis C virus infection. While T-helper type 1 cytokines are required for host …

Decreased frequency of HCV core-specific peripheral blood mononuclear cells with type 1 cytokine secretion in chronic hepatitis C

M Lechmann, RP Woitas, B Langhans, R Kaiser… - Journal of …, 1999 - Elsevier
Background/Aim: Since the outcome of hepatitis C infection appears to be correlated with
the immune response to the HCV core protein, the aim of this study was to investigate the T …

Relationship between interferon-γ, interleukin-10, and interleukin-12 production in chronic hepatitis C and in vitro effects of interferon-α

G Piazzolla, C Tortorella, O Schiraldi… - Journal of clinical …, 2000 - Springer
In the current study, increased interferon (IFN)-γ, interleukin (IL)-10, and IL-12 p40 serum
levels were observed in patients with chronic hepatitis C (CHC) compared to controls …

Polymorphisms in interleukin‐10 and interleukin‐28 B genes in E gyptian patients with chronic hepatitis C virus genotype 4 and their effect on the response to …

OG Shaker, NAH Sadik - Journal of gastroenterology and …, 2012 - Wiley Online Library
Abstract Background and Aim Recently, it has been suggested that single nucleotide
polymorphisms (SNPs) in some cytokine genes may influence the production of the …