[HTML][HTML] Going below and beyond the surface: Microneedle structure, materials, drugs, fabrication, and applications for wound healing and tissue regeneration

S Lyu, Z Dong, X Xu, HP Bei, HY Yuen, CWJ Cheung… - Bioactive materials, 2023 - Elsevier
Microneedle, as a novel drug delivery system, has attracted widespread attention due to its
non-invasiveness, painless and simple administration, controllable drug delivery, and …

Beneath the skin: a review of current trends and future prospects of transdermal drug delivery systems

AZ Alkilani, J Nasereddin, R Hamed, S Nimrawi… - Pharmaceutics, 2022 - mdpi.com
The ideal drug delivery system has a bioavailability comparable to parenteral dosage forms
but is as convenient and easy to use for the patient as oral solid dosage forms. In recent …

A touch-actuated glucose sensor fully integrated with microneedle array and reverse iontophoresis for diabetes monitoring

Y Cheng, X Gong, J Yang, G Zheng, Y Zheng… - Biosensors and …, 2022 - Elsevier
The development of non-invasive biosensor for monitoring glucose in interstitial fluid (ISF) is
still challenging, because ISF extraction through classical reverse iontophoresis (RI) is …

Wearable Clinic: From Microneedle‐Based Sensors to Next‐Generation Healthcare Platforms

H Sun, Y Zheng, G Shi, H Haick, M Zhang - Small, 2023 - Wiley Online Library
The rapid development of wearable biosensing calls for next‐generation devices that allow
continuous, real‐time, and painless monitoring of health status along with responsive …

Bioinspired microneedle patches: Biomimetic designs, fabrication, and biomedical applications

P Makvandi, A Maleki, M Shabani, ARJ Hutton… - Matter, 2022 - cell.com
Nature contains abundant systems that can significantly alter their structures and properties
to adapt to the surrounding environment. Through natural selection and unceasing …

Microneedles: a new generation vaccine delivery system

I Menon, P Bagwe, KB Gomes, L Bajaj, R Gala… - Micromachines, 2021 - mdpi.com
Transdermal vaccination route using biodegradable microneedles is a rapidly progressing
field of research and applications. The fear of painful needles is one of the primary reasons …

Hyaluronic acid based microneedle array: Recent applications in drug delivery and cosmetology

I Saha, VK Rai - Carbohydrate Polymers, 2021 - Elsevier
Microneedles are micron-sized arrays of needles that facilitate drug delivery for local and
systemic effects. Hyaluronic acid (HA) is a glycosaminoglycan and is an indigenous …

Recent advancements in microneedle technology for multifaceted biomedical applications

D Kulkarni, F Damiri, S Rojekar, M Zehravi… - Pharmaceutics, 2022 - mdpi.com
Microneedle (MNs) technology is a recent advancement in biomedical science across the
globe. The current limitations of drug delivery, like poor absorption, low bioavailability …

Advances of microneedles in biomedical applications

J Xu, D Xu, X Xuan, H He - Molecules, 2021 - mdpi.com
A microneedle (MN) is a painless and minimally invasive drug delivery device initially
developed in 1976. As microneedle technology evolves, microneedles with different shapes …

A review of 3D-printing of microneedles

M Olowe, SK Parupelli, S Desai - Pharmaceutics, 2022 - mdpi.com
Microneedles are micron-sized devices that are used for the transdermal administration of a
wide range of active pharmaceutics substances with minimally invasive pain. In the past …