Hormones are largely responsible for the integrated communication of several physiological
systems responsible for modulating cellular growth and development. Although the specific …

Corticosteroids are a class of steroid hormones released by the adrenal cortex, which
includes glucocorticoids and mineralocorticoids. 1 However, the term “corticosteroids” is …

Glucocorticoid hormones (cortisol and corticosterone-CORT) are the effector hormones of
the hypothalamic-pituitary-adrenal (HPA) axis neuroendocrine system. CORT is a systemic …

Glucocorticoids are primary stress hormones necessary for life that regulate numerous
physiologic processes in an effort to maintain homeostasis. Synthetic derivatives of these …

Glucocorticoids are among the most prescribed drugs worldwide for the treatment of
numerous immune and inflammatory disorders. They exert their actions by binding to the …

Glucocorticoids regulate numerous physiological processes and are mainstays in the
treatment of inflammation, autoimmune disease, and cancer. The traditional view that …

The nuclear receptor PPARα is associated with reducing adiposity, especially in the liver,
where it transactivates genes for β-oxidation. Contrarily, the function of PPARα in …

Numerous clinical and population studies have demonstrated that increased serum bilirubin
levels protect against cardiovascular and metabolic diseases such as obesity and diabetes …

Asthma patients are classified by phenotype and endotype. Although symptoms in most
asthma patients are well controlled by glucocorticoid treatment, certain populations of …

Adverse environments during the fetal and neonatal development period may permanently
program physiology and metabolism, and lead to increased risk of diseases in later life …