[HTML][HTML] Fatty acids and evolving roles of their proteins in neurological, cardiovascular disorders and cancers
The dysregulation of fat metabolism is involved in various disorders, including
neurodegenerative, cardiovascular, and cancers. The uptake of long-chain fatty acids …
neurodegenerative, cardiovascular, and cancers. The uptake of long-chain fatty acids …
Discerning molecular interactions: a comprehensive review on biomolecular interaction databases and network analysis tools
Computational analysis of biomolecular interaction networks is now gaining a lot of
importance to understand the functions of novel genes/proteins. Gene interaction (GI) …
importance to understand the functions of novel genes/proteins. Gene interaction (GI) …
[HTML][HTML] Targeted Inhibition of LPL/FABP4/CPT1 fatty acid metabolic axis can effectively prevent the progression of nonalcoholic steatohepatitis to liver cancer
H Yang, Q Deng, T Ni, L Lu, H Dai… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Abstract Rationale: Nonalcoholic steatohepatitis (NASH), as one of the key stages in the
development of nonalcoholic fatty liver disease (NAFLD), can directly progress to HCC, but …
development of nonalcoholic fatty liver disease (NAFLD), can directly progress to HCC, but …
FABP4 promotes invasion and metastasis of colon cancer by regulating fatty acid transport
W Tian, W Zhang, Y Zhang, T Zhu, Y Hua, H Li… - Cancer Cell …, 2020 - Springer
Background The prognosis of colon cancer is poor for metastasis, while the mechanism,
especially adipocytes related, is not yet clear. The purpose of this study is to determine the …
especially adipocytes related, is not yet clear. The purpose of this study is to determine the …
Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. An update from 2017 to early 2022
The fatty acid binding protein 4 (FABP4) is a protein predominantly expressed in
macrophages and adipose tissue, where it regulates fatty acids storage and lipolysis and is …
macrophages and adipose tissue, where it regulates fatty acids storage and lipolysis and is …
Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review
G Floresta, V Pistarà, E Amata, M Dichiara… - European journal of …, 2017 - Elsevier
Small molecule inhibitors of adipocyte fatty acid binding protein 4 (FABP4) have attracted
interest following the recent publications of beneficial pharmacological effects of these …
interest following the recent publications of beneficial pharmacological effects of these …
Milk's role as an epigenetic regulator in health and disease
BC Melnik, G Schmitz - Diseases, 2017 - mdpi.com
It is the intention of this review to characterize milk's role as an epigenetic regulator in health
and disease. Based on translational research, we identify milk as a major epigenetic …
and disease. Based on translational research, we identify milk as a major epigenetic …
Gene interaction network studies to decipher the multi-drug resistance mechanism in Salmonella enterica serovar Typhi CT18 reveal potential drug targets
Salmonella enterica subsp. enterica serovar Typhi, a human enteric pathogen causing
typhoid fever, developed resistance to multiple antibiotics over the years. The current study …
typhoid fever, developed resistance to multiple antibiotics over the years. The current study …
[HTML][HTML] Exploring the multi-drug resistance in Escherichia coli O157: H7 by gene interaction network: a systems biology approach
SK Miryala, S Ramaiah - Genomics, 2019 - Elsevier
In the present study, we have constructed an interaction network of 29 antibiotic resistant
genes along with 777 interactions in E. coli O157: H7. Gene ontology analysis reveals that …
genes along with 777 interactions in E. coli O157: H7. Gene ontology analysis reveals that …
[HTML][HTML] Pharmacologic activation of estrogen receptor β increases mitochondrial function, energy expenditure, and brown adipose tissue
S Ponnusamy, QT Tran, I Harvey… - The FASEB …, 2017 - ncbi.nlm.nih.gov
Most satiety-inducing obesity therapeutics, despite modest efficacy, have safety concerns
that underscore the need for effective peripherally acting drugs. An attractive therapeutic …
that underscore the need for effective peripherally acting drugs. An attractive therapeutic …