In this Review, I present evidence supporting a multifactorial causation of childhood acute
lymphoblastic leukaemia (ALL), a major subtype of paediatric cancer. ALL evolves in two …

Background Birth weight, a marker of the intrauterine environment, has been extensively
studied in epidemiological research in relation to subsequent health and disease. Although …

In this article, the American Cancer Society provides estimates of the number of new cancer
cases and deaths for children and adolescents in the United States and summarizes the …

The causes of childhood cancer have been systematically studied for several decades, but
apart from high-dose radiation and prior chemotherapy there are few or no strong external …

Background The role that pesticides in the domestic environment might play in the etiology
of childhood leukemia remains a subject of controversy. Recent studies often reached …

Incidence rates of childhood leukemia in the United States have steadily increased over the
last several decades, but only recently have disparities in the increase in incidence been …

Simple Summary Leukemia is the most common type of cancer among children worldwide.
The aim of this umbrella review was to provide an evidence-based summary of …

Infants and children are particularly vulnerable to in utero and early-life exposures. Thus, a
mother's exposures before and during pregnancy could have important consequences for …

Advanced parental age has been associated with adverse health effects in the offspring
including childhood (0–14 years) acute lymphoblastic leukemia (ALL), as reported in our …

Increasing evidence suggests that breastfeeding may protect from childhood acute
lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). However, most studies …