Strategies for large-scale targeted metabolomics quantification by liquid chromatography-mass spectrometry

J Zhou, Y Yin - Analyst, 2016 - pubs.rsc.org
Advances in liquid chromatography-mass spectrometry (LC-MS) instruments and analytical
strategies have brought about great progress in targeted metabolomics analysis. This …

Current state-of-the-art of nontargeted metabolomics based on liquid chromatography–mass spectrometry with special emphasis in clinical applications

P Yin, G Xu - Journal of Chromatography A, 2014 - Elsevier
Metabolomics, as a part of systems biology, has been widely applied in different fields of life
science by studying the endogenous metabolites. The development and applications of …

Multi-analyte high performance liquid chromatography coupled to high resolution tandem mass spectrometry method for control of pesticide residues, mycotoxins, and …

Z Dzuman, M Zachariasova, Z Veprikova, M Godula… - Analytica Chimica …, 2015 - Elsevier
A new reliable and highly sensitive method based on high performance liquid
chromatographic (HPLC) separation and high resolution tandem mass spectrometric …

An enhanced sensitivity and cleanup strategy for the nontargeted screening and targeted determination of pesticides in tea using modified dispersive solid-phase …

F Wang, S Li, H Feng, Y Yang, B Xiao, D Chen - Food chemistry, 2019 - Elsevier
At present, matrix interferences in tea are still a great challenge for analysis of multi-
pesticide residues. Herein, a simple sample preparation method was developed based on …

Targeted analysis of multiple pharmaceuticals, plant toxins and other secondary metabolites in herbal dietary supplements by ultra-high performance liquid …

L Vaclavik, AJ Krynitsky, JI Rader - Analytica chimica acta, 2014 - Elsevier
In this study, an ultra-high performance liquid chromatography–quadrupole-orbital ion trap
mass spectrometry (UHPLC–Q-orbitrap MS) method was developed and validated for …

Metabolomics in hepatocellular carcinoma: From biomarker discovery to precision medicine

X Wu, Z Wang, L Luo, D Shu, K Wang - Frontiers in Medical …, 2023 - frontiersin.org
Hepatocellular carcinoma (HCC) remains a global health burden, and is mostly diagnosed
at late and advanced stages. Currently, limited and insensitive diagnostic modalities …

A comparison of four liquid chromatography–mass spectrometry platforms for the analysis of zeranols in urine

A Lazofsky, A Brinker, Z Rivera-Núñez… - Analytical and …, 2023 - Springer
Targeted biomonitoring studies quantifying the concentration of zeranols in biological
matrices have focused on liquid chromatography interfaced to mass spectrometry (LC–MS) …

Large pesticide multiresidue screening method by liquid chromatography-Orbitrap mass spectrometry in full scan mode applied to fruit and vegetables

Ł Rajski, M del Mar Gómez-Ramos… - … of Chromatography A, 2014 - Elsevier
The present work is focused on evaluating the main operational parameters for multiresidue
screening of an Orbitrap mass spectrometer for pesticide residue analysis in fruits and …

Multi-residue pesticide analysis in virgin olive oil by nanoflow liquid chromatography high resolution mass spectrometry

D Moreno-González, J Alcántara-Durán… - … of Chromatography A, 2018 - Elsevier
In this article, a nanoflow liquid chromatography system coupled to high resolution mass
spectrometry (nanoflow LC/ESI Q-Orbitrap-MS) has been applied for the development of a …

Evaluation of nanoflow liquid chromatography high resolution mass spectrometry for pesticide residue analysis in food

D Moreno-González, P Pérez-Ortega… - … of Chromatography A, 2017 - Elsevier
This article reports on the evaluation of nanoflow liquid chromatography-mass spectrometry
(LC–MS) for pesticide residue analysis in food. The approach is based on the use of …