Somatostatin analogs in clinical practice: a review

M Gomes-Porras, J Cárdenas-Salas… - International journal of …, 2020 - mdpi.com
Somatostatin analogs are an invaluable therapeutic option in the diagnosis and treatment of
somatotropinomas, thyrotropinomas, and functioning and non-functioning …

International Union of Basic and Clinical Pharmacology. CV. Somatostatin receptors: structure, function, ligands, and new nomenclature

T Günther, G Tulipano, P Dournaud, C Bousquet… - Pharmacological …, 2018 - ASPET
Somatostatin, also known as somatotropin-release inhibitory factor, is a cyclopeptide that
exerts potent inhibitory actions on hormone secretion and neuronal excitability. Its …

The North American neuroendocrine tumor society consensus guidelines for surveillance and medical management of pancreatic neuroendocrine tumors

TR Halfdanarson, JR Strosberg, L Tang, AM Bellizzi… - Pancreas, 2020 - journals.lww.com
This article is the result of the North American Neuroendocrine Tumor Society consensus
conference on the medical management of pancreatic neuroendocrine tumors from July 19 …

Immunohistochemistry in the diagnosis and classification of neuroendocrine neoplasms: what can brown do for you?

AM Bellizzi - Human pathology, 2020 - Elsevier
This review is based on a presentation given at the Hans Popper Hepatopathology Society
companion meeting at the 2019 United States and Canadian Academy of Pathology Annual …

Pancreatic neuroendocrine tumors: molecular mechanisms and therapeutic targets

CK Maharjan, PH Ear, CG Tran, JR Howe… - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic neuroendocrine tumors (pNETs) are rare, indolent cancers
whose causation is only partly understood. An increasing number of studies have uncovered …

Epigenetic regulation of somatostatin and somatostatin receptors in neuroendocrine tumors and other types of cancer

MJ Klomp, SU Dalm, M De Jong, RA Feelders… - Reviews in Endocrine …, 2021 - Springer
Both somatostatin (SST) and somatostatin receptors (SSTRs) are proteins with important
functions in both physiological tissue and in tumors, particularly in neuroendocrine tumors …

Neuroendocrine neoplasms in the context of inherited tumor syndromes: a reappraisal focused on targeted therapies

RM Ruggeri, E Benevento, F De Cicco… - Journal of …, 2023 - Springer
Purpose Neuroendocrine neoplasms can occur as part of inherited disorders, usually in the
form of well-differentiated, slow-growing tumors (NET). The main predisposing syndromes …

Immunohistochemical biomarkers of gastrointestinal, pancreatic, pulmonary, and thymic neuroendocrine neoplasms

S Uccella, S La Rosa, M Volante, M Papotti - Endocrine pathology, 2018 - Springer
Neuroendocrine neoplasms (NENs) are a heterogeneous group of epithelial neoplastic
proliferations that irrespective of their primary site share features of neural and endocrine …

[HTML][HTML] Inter and intra-tumor somatostatin receptor 2 heterogeneity influences peptide receptor radionuclide therapy response

D Feijtel, GN Doeswijk, NS Verkaik, JC Haeck… - Theranostics, 2021 - ncbi.nlm.nih.gov
Patients with neuroendocrine tumors (NETs) can be treated with peptide receptor
radionuclide therapy (PRRT). Here, the somatostatin analogue octreotate radiolabeled with …

Theranostics in neuroendocrine tumors: an overview of current approaches and future challenges

J Refardt, J Hofland, A Kwadwo, GP Nicolas… - Reviews in Endocrine …, 2021 - Springer
Neuroendocrine neoplasms (NENs) comprise a heterogeneous group of tumors, mainly
localized in the gastrointestinal system. What characterizes NENs is the expression of …