Roles of the microbiota of the female reproductive tract in gynecological and reproductive health

B Zhu, Z Tao, L Edupuganti, MG Serrano… - … and Molecular Biology …, 2022 - Am Soc Microbiol
The microbiome of the female reproductive tract defies the convention that high biodiversity
is a hallmark of an optimal ecosystem. Although not universally true, a homogeneous …

Fighting polymicrobial biofilms in bacterial vaginosis

LGV Sousa, SA Pereira, N Cerca - Microbial Biotechnology, 2023 - Wiley Online Library
Bacterial vaginosis (BV) is the most common cause of vaginal discharge and is often
associated with other health consequences mainly in pregnant women. BV is described by …

Gardnerella Revisited: Species Heterogeneity, Virulence Factors, Mucosal Immune Responses, and Contributions to Bacterial Vaginosis

E Shvartsman, JE Hill, P Sandstrom… - Infection and …, 2023 - Am Soc Microbiol
Gardnerella species are associated with bacterial vaginosis (BV) and have been
investigated as etiological agents of the condition. Nonetheless, the isolation of this taxon …

Association of key species of vaginal bacteria of recurrent bacterial vaginosis patients before and after oral metronidazole therapy with short-and long-term clinical …

A Mollin, M Katta, JD Sobel, RA Akins - PLoS One, 2022 - journals.plos.org
Bacterial vaginosis (BV) is associated with a state of vaginal dysbiosis typically involving
depletion of otherwise dominant populations of Lactobacillus. The causes of this microbial …

Tilapia Piscidin 4 (TP4) Reprograms M1 Macrophages to M2 Phenotypes in Cell Models of Gardnerella vaginalis-Induced Vaginosis

CW Liu, BC Su, JY Chen - Frontiers in Immunology, 2021 - frontiersin.org
Gardnerella vaginalis is associated with bacterial vaginosis (BV). The virulence factors
produced by G. vaginalis are known to stimulate vaginal mucosal immune response, which …

Nuclear magnetic resonance metabolomics of symbioses between bacterial vaginosis-associated bacteria

V Horrocks, CK Hind, ME Wand, PE Fady, J Chan… - MSphere, 2022 - Am Soc Microbiol
Bacterial vaginosis (BV) is a dysbiosis of the vaginal microbiome, characterized by low
levels of lactobacilli and overgrowth of a diverse group of bacteria, associated with higher …

Diversity of β‐hemolysins produced by the human opportunistic streptococci

A Tabata, H Nagamune - Microbiology and Immunology, 2021 - Wiley Online Library
The genus Streptococcus infects a broad range of hosts, including humans. Some species,
such as S. pyogenes, S. agalactiae, S. pneumoniae, and S. mutans, are recognized as the …

Gardnerella pickettii sp. nov. (formerly Gardnerella genomic species 3) and Gardnerella greenwoodii sp. nov. (formerly Gardnerella genomic species 8) isolated …

M Sousa, M Ksiezarek, SU Perovic… - … of Systematic and …, 2023 - microbiologyresearch.org
During an ongoing female urinary microbiome research study, strains c17Ua_112T and
c31Ua_26T isolated from urine samples of a patient diagnosed with overactive bladder and …

Phase variable colony variants are conserved across Gardnerella spp. and exhibit different virulence-associated phenotypes

EM Garcia, AK Klimowicz, L Edupuganti, MA Topf… - mSphere, 2024 - Am Soc Microbiol
The Gardnerella genus, comprising at least 13 species, is associated with the polymicrobial
disorder bacterial vaginosis (BV). However, the details of BV pathogenesis are poorly …

Does Bacterial Vaginosis Contribute to Urinary Tract Infection?

VL Handa, RM Brotman, J Ravel… - Current Infectious Disease …, 2023 - Springer
Abstract Purpose of Review Antibiotic-sparing therapies to treat and prevent urinary tract
infections (UTIs) are needed. Interest surrounds the question of whether bacterial vaginosis …