Diabetes mellitus is one of the major health problems in the world, the incidence and
associated mortality are increasing. Inadequate regulation of the blood sugar imposes …

The dynamic and delicate interactions amongst intestinal microbiota, metabolome and
metabolism dictates human health and disease. In recent years, our understanding of gut …

Gum arabica is a local commercial nutraceutical and food preservative collected mostly from
acacia plants. HPLC-DAD analysis identified gallic acid, syringic acid, ferulic acid, coumarin …

Abstract Globally, diabetes causes about 1.5 million deaths per year. Data predicts that the
current global epidemiological burden of diabetes is increasing alongside its long-term life …

Ethnopharmacological relevance The global problem of diabetes, together with the limited
access of large numbers of patients to conventional antidiabetic medicines, continues to …

Diabetes mellitus (DM), a chronic medical condition, has attained a global pandemic status
over the last few decades affecting millions of people. Despite a variety of synthetic drugs …

Aims The present experiment was conceptualised to explore the therapeutic response of
tetramethylpyrazine (TMP), a major active constituent of Ligusticum chuanxiong, a Chinese …

Centering around the concept that metabolites from the gut commensals can exert metabolic
health benefits along the gut–liver axis, we tested whether the cell-free global metabolome …

This study aimed to investigate the therapeutic effect of curcumin on type 2 diabetes and its
underlying mechanisms. A type 2 diabetes mellitus rat model was established by providing …

The role of gut microbiome in human health and disease is well established. While evidence-
based pharmacological studies utilize a variety of chemical-induced metabolic and …