Pneumococcal meningitis continues to be associated with high rates of mortality and long-
term neurological sequelae. The most common route of infection starts by nasopharyngeal …

Bacterial infection of the central nervous system (CNS) is a life-threatening condition with a
high mortality. Antibiotic therapy and vaccines have changed the face of bacterial CNS …

Background Pneumococcal meningitis is associated with high risk of neurological sequelae
such as cognitive impairment and hearing loss. These sequelae are due to parenchymal …

Bacterial meningitis is associated with high mortality and morbidity rates. Bacterial
components induce an overshooting inflammatory reaction, eventually leading to brain …

We verify the levels of cytokine/chemokine, myeloperoxidase activity, oxidative stress and
disruption of BBB in hippocampus and cortex of the neonate Wistar rats after meningitis by …

Background Pneumococcal meningitis is associated with high mortality and morbidity rates.
Up to 50% of survivors show neurologic sequelae including hearing loss, cognitive …

Bacterial meningitis (BM) is a life-threatening disease characterized by an acute purulent
infection of the pia, the arachnoid, and the subarachnoid space. 1 The resulting …

Reactive oxygen species (ROS) that form in the inner ear play an important role in noise-
induced hearing loss (NIHL). Recent studies have revealed that molecular hydrogen (H 2) …

Abstract Background. Group B Streptococcus (GBS) and Streptococcus pneumoniae (SP)
are leading causes of bacterial meningitis in neonates and children. Each pathogen …

Hearing loss is an important sequela of pneumococcal meningitis (PM), occurring in up to
30% of survivors. The role of the severity of infection on hearing function and …