Implant infections: adhesion, biofilm formation and immune evasion

CR Arciola, D Campoccia, L Montanaro - Nature reviews microbiology, 2018 - nature.com
Medical device-associated infections account for a large proportion of hospital-acquired
infections. A variety of opportunistic pathogens can cause implant infections, depending on …

Staphylococcus aureus biofilm: a complex developmental organism

DE Moormeier, KW Bayles - Molecular microbiology, 2017 - Wiley Online Library
Chronic biofilm‐associated infections caused by Staphylococcus aureus often lead to
significant increases in morbidity and mortality, particularly when associated with indwelling …

A review of the biomaterials technologies for infection-resistant surfaces

D Campoccia, L Montanaro, CR Arciola - Biomaterials, 2013 - Elsevier
Anti-infective biomaterials need to be tailored according to the specific clinical application.
All their properties have to be tuned to achieve the best anti-infective performance together …

Antifouling and antimicrobial biomaterials: an overview

I Francolini, C Vuotto, A Piozzi, G Donelli - Apmis, 2017 - Wiley Online Library
The use of implantable medical devices is a common and indispensable part of medical
care for both diagnostic and therapeutic purposes. However, as side effect, the implant of …

Biofilm formation in Staphylococcus implant infections. A review of molecular mechanisms and implications for biofilm-resistant materials

CR Arciola, D Campoccia, P Speziale, L Montanaro… - Biomaterials, 2012 - Elsevier
Implant infections in orthopaedics, as well as in many other medical fields, are chiefly
caused by staphylococci. The ability of growing within a biofilm enhances the chances of …

The role of microbial biofilms in prosthetic joint infections: A review

HO Gbejuade, AM Lovering, JC Webb - Acta orthopaedica, 2015 - Taylor & Francis
Prosthetic joint infection (PJI) still remains a significant problem. In line with the forecasted
rise in joint replacement procedures, the number of cases of PJI is also anticipated to rise …

The effect of bacterial chemotaxis on host infection and pathogenicity

MA Matilla, T Krell - FEMS Microbiology Reviews, 2018 - academic.oup.com
Chemotaxis enables microorganisms to move according to chemical gradients. Although
this process requires substantial cellular energy, it also affords key physiological benefits …

Scenery of Staphylococcus Implant Infections in Orthopedics

L Montanaro, P Speziale, D Campoccia… - Future …, 2011 - Taylor & Francis
Infection is still the major complication of orthopedic implants and projections based on the
actual trend indicate that total hip and knee arthroplasties and their consequent infection …

A review of the clinical implications of anti-infective biomaterials and infection-resistant surfaces

D Campoccia, L Montanaro, CR Arciola - Biomaterials, 2013 - Elsevier
Infection is currently regarded as the most severe and devastating complication associated
to the use of biomaterials. The important social, clinical and economic impacts of implant …

The Multivalent Role of Fibronectin-Binding Proteins A and B (FnBPA and FnBPB) of Staphylococcus aureus in Host Infections

P Speziale, G Pietrocola - Frontiers in microbiology, 2020 - frontiersin.org
Staphylococcus aureus, one of the most important human pathogens, is the causative agent
of several infectious diseases including sepsis, pneumonia, osteomyelitis, endocarditis and …