Childhood socio-economic status (SES), a measure of the availability of material and social
resources, is one of the strongest predictors of lifelong well-being. Here we review evidence …

Gender is not accurately captured by the traditional male and female dichotomy of sex.
Instead, it is a complex social system that structures the life experience of all human beings …

DNA methylation is the most well studied of the epigenetic regulators in relation to
environmental exposures. To date, numerous studies have detailed the manner by which …

The process of aging results in a host of changes at the cellular and molecular levels, which
include senescence, telomere shortening, and changes in gene expression. Epigenetic …

Background It is not yet known whether DNA methylation levels can be used to accurately
predict age across a broad spectrum of human tissues and cell types, nor whether the …

Because of the dearth of biomarkers of aging, it has been difficult to test the hypothesis that
obesity increases tissue age. Here we use a novel epigenetic biomarker of aging (referred to …

Validated biological and psychological markers of acute stress in humans are an important
tool in translational research. The Trier Social Stress Test (TSST), involving public interview …

Biological embedding occurs when life experience alters biological processes to affect later
life health and well-being. Although extensive correlative data exist supporting the notion …

Objective Differential effects of maternal and paternal posttraumatic stress disorder (PTSD)
have been observed in adult offspring of Holocaust survivors in both glucocorticoid receptor …

Background Human aging is associated with DNA methylation changes at specific sites in
the genome. These epigenetic modifications may be used to track donor age for forensic …