Mice alternate between discrete strategies during perceptual decision-making

ZC Ashwood, NA Roy, IR Stone… - Nature …, 2022 - nature.com
Classical models of perceptual decision-making assume that subjects use a single,
consistent strategy to form decisions, or that decision-making strategies evolve slowly over …

[HTML][HTML] Trial-history biases in evidence accumulation can give rise to apparent lapses in decision-making

D Gupta, B DePasquale, CD Kopec… - Nature communications, 2024 - nature.com
Trial history biases and lapses are two of the most common suboptimalities observed during
perceptual decision-making. These suboptimalities are routinely assumed to arise from …

Finding the brain in the nose

DH Brann, SR Datta - Annual Review of Neuroscience, 2020 - annualreviews.org
Olfaction is fundamentally distinct from other sensory modalities. Natural odor stimuli are
complex mixtures of volatile chemicals that interact in the nose with a receptor array that, in …

[HTML][HTML] Standardized and reproducible measurement of decision-making in mice

International Brain Laboratory, V Aguillon-Rodriguez… - Elife, 2021 - elifesciences.org
Progress in science requires standardized assays whose results can be readily shared,
compared, and reproduced across laboratories. Reproducibility, however, has been a …

[HTML][HTML] Reinforcement biases subsequent perceptual decisions when confidence is low, a widespread behavioral phenomenon

A Lak, E Hueske, J Hirokawa, P Masset, T Ott, AE Urai… - Elife, 2020 - elifesciences.org
Learning from successes and failures often improves the quality of subsequent decisions.
Past outcomes, however, should not influence purely perceptual decisions after task …

Strategically managing learning during perceptual decision making

J Masís, T Chapman, JY Rhee, DD Cox, AM Saxe - Elife, 2023 - elifesciences.org
Making optimal decisions in the face of noise requires balancing short-term speed and
accuracy. But a theory of optimality should account for the fact that short-term speed can …

Optimal policy for multi-alternative decisions

S Tajima, J Drugowitsch, N Patel, A Pouget - Nature neuroscience, 2019 - nature.com
Everyday decisions frequently require choosing among multiple alternatives. Yet the optimal
policy for such decisions is unknown. Here we derive the normative policy for general multi …

[HTML][HTML] Lapses in perceptual decisions reflect exploration

S Pisupati, L Chartarifsky-Lynn, A Khanal… - Elife, 2021 - elifesciences.org
Perceptual decision-makers often display a constant rate of errors independent of evidence
strength. These 'lapses' are treated as a nuisance arising from noise tangential to the …

The mechanistic foundation of Weber's law

JL Pardo-Vazquez, JR Castiñeiras-de Saa… - Nature …, 2019 - nature.com
Although Weber's law is the most firmly established regularity in sensation, no principled
way has been identified to choose between its many proposed explanations. We …

Brain-wide representations of prior information in mouse decision-making

C Findling, F Hubert, International Brain Laboratory… - BioRxiv, 2023 - biorxiv.org
The neural representations of prior information about the state of the world are poorly
understood. To investigate this issue, we examined brain-wide Neuropixels recordings and …