[HTML][HTML] Coumarin: A natural, privileged and versatile scaffold for bioactive compounds
A Stefanachi, F Leonetti, L Pisani, M Catto, A Carotti - Molecules, 2018 - mdpi.com
Many naturally occurring substances, traditionally used in popular medicines around the
world, contain the coumarin moiety. Coumarin represents a privileged scaffold for medicinal …
world, contain the coumarin moiety. Coumarin represents a privileged scaffold for medicinal …
Transition metal-catalyzed double C vinyl–H bond activation: synthesis of conjugated dienes
VK Maikhuri, J Maity, S Srivastava… - Organic & Biomolecular …, 2022 - pubs.rsc.org
Conjugated dienes have occupied a pivotal position in the field of synthetic organic
chemistry and medicinal chemistry. They act as important synthons for the synthesis of …
chemistry and medicinal chemistry. They act as important synthons for the synthesis of …
Metal-free oxidative coupling of quinoxalin-2 (1 H)-ones with arylaldehydes leading to 3-acylated quinoxalin-2 (1 H)-ones
JW Yuan, JH Fu, SN Liu, YM Xiao, P Mao… - Organic & Biomolecular …, 2018 - pubs.rsc.org
A facile TBHP-mediated direct oxidative coupling of quinoxalin-2 (1H)-ones with
arylaldehydes has been developed under metal-free conditions. This method provided a …
arylaldehydes has been developed under metal-free conditions. This method provided a …
Visible-Light-Induced Regioselective Alkylation of Coumarins via Decarboxylative Coupling with N-Hydroxyphthalimide Esters
C Jin, Z Yan, B Sun, J Yang - Organic letters, 2019 - ACS Publications
An efficient photocatalytic decarboxylative 3-position alkylation of coumarins by using alkyl
N-hydroxyphthalimide esters as alkylation reagents has been developed. A variety of NHP …
N-hydroxyphthalimide esters as alkylation reagents has been developed. A variety of NHP …
Metal-free regioselective C–H chalcogenylation of coumarins/(hetero) arenes at ambient temperature
Z Song, C Ding, S Wang, Q Dai, Y Sheng… - Chemical …, 2020 - pubs.rsc.org
A novel, practical and metal-free approach for the regioselective selenation of coumarins
employing (bis (trifluoroacetoxy) iodo) benzene (PIFA) at room temperature is presented …
employing (bis (trifluoroacetoxy) iodo) benzene (PIFA) at room temperature is presented …
Visible Light‐Induced Regioselective Decarboxylative Alkylation of the C(sp2)−H Bonds of Non‐Aromatic Heterocycles
L Liu, N Pan, W Sheng, L Su, L Liu… - Advanced Synthesis …, 2019 - Wiley Online Library
With sunlight or blue LEDs irradiation, regioselective decarboxylative alkylation of various
non‐aromatic heterocycles has been realized via C (sp3)‐centered radical C (sp2)− C (sp3) …
non‐aromatic heterocycles has been realized via C (sp3)‐centered radical C (sp2)− C (sp3) …
Visible-light-driven copper-catalyzed aerobic oxidative cascade cyclization of N-tosylhydrazones and terminal alkynes: regioselective synthesis of 3-arylcoumarins
V PramodáCharpe, K ChuáHwang - Chemical Communications, 2019 - pubs.rsc.org
We present the first example of sustainable, intuitive, highly regioselective, visible-light-
driven copper catalyzed aerobic oxidative cascade cyclization of N-tosylhydrazones with …
driven copper catalyzed aerobic oxidative cascade cyclization of N-tosylhydrazones with …
Access to 4-alkenylated coumarins via ruthenium-catalyzed olefinic C–H alkenylation of coumarins with modifiable and removable directing groups
YJ Wang, TT Wang, L Yao, QL Wang… - The Journal of Organic …, 2020 - ACS Publications
The ruthenium-catalyzed activation of the C4 position of coumarins for coupling with
acrylates was described using modifiable ketone as a directing group. The alkenylation …
acrylates was described using modifiable ketone as a directing group. The alkenylation …
Dual role of oxoaldehydes: Divergent synthesis of 3-aryl-and 3-aroylcoumarins
A Moazzam, M Khodadadi, F Jafarpour… - The Journal of Organic …, 2022 - ACS Publications
A facile and efficient synthetic approach to various valuable 3-aryl-and 3-aroylcoumarins by
the direct arylation and aroylation of coumarins with glyoxals in a metal-free manner is …
the direct arylation and aroylation of coumarins with glyoxals in a metal-free manner is …
Chlorophyll-catalyzed photochemical regioselective coumarin C–H arylation with diazonium salts
A Moazzam, F Jafarpour - New Journal of Chemistry, 2020 - pubs.rsc.org
This communication describes the development of a mild method for the cross-coupling of
the C3-position of coumarin with an array of diazonium salts mediated by chlorophyll as a …
the C3-position of coumarin with an array of diazonium salts mediated by chlorophyll as a …