Obesity is a growing health problem worldwide. It is associated with an increased
cardiovascular risk on the one hand of obesity itself and on the other hand of associated …

Mitral regurgitation affects more than 2 million people in the USA. The main causes are
classified as degenerative (with valve prolapse) and ischaemic (ie, due to consequences of …

1.1. Organization of Committee and Evidence Review (UPDATED) For new or updated text,
view the 2011 Focused Update and the 2011 Update on Dabigatran. Text supporting …

Background The natriuretic peptides are counterregulatory hormones involved in volume
homeostasis and cardiovascular remodeling. The prognostic significance of plasma …

Atrial fibrillation (AF) is the most common sustained cardiac rhythm disturbance, increasing
in prevalence with age. AF is often associated with structural heart disease, although a …

Background—Atrial fibrillation (AF), the most common cardiac rhythm abnormality, is
associated with significant morbidity, mortality, and healthcare expenditures. Elevated B …

Structural remodelling occurring before, due to the underlying heart disease, and during
atrial fibrillation (AF) sets the stage for permanent AF. Current therapy in AF aims to maintain …

Objectives: This study was conducted to define the association between serum B-type
natriuretic peptide (BNP) activation and survival after the diagnosis of aortic stenosis (AS) …

Atrial enlargement in response to pathological stimuli (eg, hypertension, mitral valve
disease) and physiological stimuli (exercise, pregnancy) can be comparable in magnitude …

Background—Structural changes, like atrial fibrosis, may increase the likelihood of atrial
fibrillation (AF) occurring in response to triggering events. The influence of isolated atrial …