Background: Thiazole and benzothiazole derivatives, as well as thiazolidinones are very
important scaffolds in medicinal chemistry. Literature has revealed that they possess a wide …

New ibuprofen derivatives containing variously substituted pyrazoline have been
synthesized, characterized by FT-IR and 1H-NMR spectroscopy and evaluated preliminarily …

The synthesis of new selective COX-2 enzyme is an approach for obtaining potent, anti-
inflammatory drugs that have fewer side effects. Ketoprofen has a very low selectivity toward …

Four different ibuprofen derivatives were synthesized by modification of the carboxyl group
to its bioisoster 1, 3, 4-oxadiazole heterocyclic ring, in which 2-position was substituted with …

Objective: The objective of this search was to synthesize a new naproxen analogues having
a 1, 2, 4-triazole-3-thiol heterocyclic ring, and preliminary pharmacological assessment of …

Thiazolidinone and its derivatives are very promising scaffolds for various biological
activities like antimicrobial, antitubercular, anticancer, anti-HIV, anti-inflammatory …

Abstract Various 2-(4'-methyl-N-phenyl substituted)-1, 1'-biphenyl-2-ylcarboxamido-2-
oxoethyl nitrate analogues were synthesized and evaluated for analgesic, anti-inflammatory …

Mefenamic acid (MA) widely used probably due to having both anti-inflammatory and
analgesic activity, the main side effects of mefenamic acid include gastrointestinal tract (GIT) …

Since many decades, causes of death due to health issues have tremendously increased
and still increasing. Deaths due to non-communicable diseases increase in India. According …

To overcome the widespread emergence of drug resistant pathological agents, newer
treatment options are required to be found urgently. This research aims to design new …