FLASH radiotherapy is the delivery of ultra-high dose rate radiation several orders of
magnitude higher than what is currently used in conventional clinical radiotherapy, and has …

Until recently, radiation effects have been considered to be mainly due to nuclear DNA
damage and their management by repair mechanisms. However, molecular biology studies …

Radiation exposures at ultrahigh dose rates (UHDRs) at several orders of magnitude greater
than in current clinical radiotherapy (RT) have been shown to manifest differential …

Background and purpose The FLASH effect is a potential breakthrough in radiotherapy
because ultra-high dose-rate irradiation can substantially widen the therapeutic window …

Background and purpose Recent observations in animal models show that ultra-high dose
rate (“FLASH”) radiation treatment significantly reduces normal tissue toxicity maintaining an …

FLASH radiotherapy is considered a new potential breakthrough in cancer treatment. Ultra‐
high dose rates (> 40 Gy/s) have been shown to reduce toxicity in the normal tissue without …

Radiation therapy, along with surgery and chemotherapy, is one of the main treatments for
cancer. While radiotherapy is highly effective in the treatment of localized tumors, its main …

Radiotherapy is the current standard of care for more than 50% of all cancer patients.
Improvements in radiotherapy (RT) technology have increased tumor targeting and normal …

Purpose To establish and investigate the effects of dose, linear energy transfer (LET), and O
2 concentration on biologic response to ultrahigh dose rate (uHDR; FLASH) helium ion …

Radiation chemists have been routinely using high-dose microsecond-pulsed irradiation for
almost 60 years, involving many thousands of studies, in the technique of “pulse radiolysis” …