Dystrophin proteomic regulation in muscular dystrophies (MDs) remains unclear. We report
that a long noncoding RNA (lncRNA), H19, associates with dystrophin and inhibits E3-ligase …

The induced pluripotent stem cells (iPSCs) are derived from somatic cells by using
reprogramming factors such as Oct4, Sox2, Klf4, and c-Myc (OSKM) or Oct4, Sox2, Nanog …

Translation of any inventions into products requires manufacturing. Development of
drug/gene/cell delivery systems will eventually face manufacturing challenges, which …

Introduction The prospect of therapeutic applications of the induced pluripotent stem cells
(iPSCs) is based on their ability to generate virtually any cell type present in human body …

We generated patient-specific disease-free induced pluripotent stem cells (iPSCs) from
peripheral blood CD34+ cells and differentiated them into functional endothelial cells (ECs) …

Human induced pluripotent stem cells (hiPSCs) are the ideal cell source for autologous cell
replacement. However, for patients with Mendelian diseases, genetic correction of the …

Human pluripotent stem cells (hPSCs) are increasingly gaining attention in biomedicine as
valuable resources to establish patient-derived cell culture models of the cell type known to …

Stem cells have recently emerged as an important candidate for cell therapy. However,
some major limitations still exist such as a small quantity of cell supply, senescence, and …

In vitro models of the neuromuscular junction (NMJ) are emerging as a valuable tool to study
synaptogenesis, synaptic maintenance, and pathogenesis of neurodegenerative diseases …

We describe an adaptation of φC31 integrase–mediated targeted cassette exchange for use
in Drosophila cell lines. Single copies of an attP-bounded docking platform carrying a GFP …