The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …

AHAs are organic acids with one hydroxyl group attached to the alpha position of the acid.
AHAs including glycolic acid, lactic acid, malic acid, tartaric acid, and citric acid are often …

Numerous physiological functions rely on distinguishing temperature through temperature-
sensitive transient receptor potential channels (thermo-TRPs). Although the function of …

The myelin sheaths wrapped around axons by oligodendrocytes are crucial for brain
function. In ischaemia myelin is damaged in a Ca2+-dependent manner, abolishing action …

In the skin, cannabinoid lipids, whether of endogenous or exogenous origin, are capable of
regulating numerous sensory, homeostatic, and inflammatory events. Although many of …

Emerging evidence suggests that transient receptor potential (TRP) ion channels not only
act as 'polymodal cellular sensors' on sensory neurons but are also functionally expressed …

The vanilloid transient receptor potential channel TRPV3 differs in several aspects from
other members of the TRPV subfamily. This Ca2+‐, ATP‐and calmodulin‐regulated channel …

Genetic gain-of-function mutations of warm temperature-sensitive transient receptor
potential vanilloid 3 (TRPV3) channel cause Olmsted syndrome characterized by severe …

Transient receptor potential vanilloid 3 (TRPV3) is a member of the TRP (Transient Receptor
Potential) super-family. It is a relatively underexplored member of the thermo-TRP sub …

Nociceptors, ie sensory neurons tuned to detect noxious stimuli, are found in numerous
phyla of the Animalia kingdom and are often polymodal, responding to a variety of stimuli, eg …