Nanoparticle drug delivery systems responsive to tumor microenvironment: Promising alternatives in the treatment of triple‐negative breast cancer
Y Cao, F Meng, T Cai, L Gao, J Lee… - Wiley …, 2024 - Wiley Online Library
The conventional therapeutic treatment of triple‐negative breast cancer (TNBC) is negatively
influenced by the development of tumor cell drug resistant, and systemic toxicity of …
influenced by the development of tumor cell drug resistant, and systemic toxicity of …
Characterization of coagulation-related gene signature to predict prognosis and tumor immune microenvironment in skin cutaneous melanoma
B Song, H Chi, G Peng, Y Song, Z Cui, Y Zhu… - Frontiers in …, 2022 - frontiersin.org
Backgroud Skin cutaneous melanoma (SKCM) is an extremely metastatic form of skin
cancer. However, there are few valuable molecular biomarkers, and accurate diagnosis is …
cancer. However, there are few valuable molecular biomarkers, and accurate diagnosis is …
FOCAD/miR-491-5p, downregulated by EGR1, function as tumor suppressor by inhibiting the proliferation and migration of gastric cancer cells
R Sun, Z Liu, Y Lv, Y Yang, Y Yang, Y Xiang… - Progress in Biophysics …, 2022 - Elsevier
Gastric cancer is a common malignant tumor in China; however, its carcinogenesis remains
unknown. Focadhesin (FOCAD) is a tumor suppressor gene in gliomas, its expression, role …
unknown. Focadhesin (FOCAD) is a tumor suppressor gene in gliomas, its expression, role …
Identification of modules and key genes associated with breast cancer subtypes through network analysis
MD Mares-Quiñones, E Galán-Vásquez… - Scientific Reports, 2024 - nature.com
Breast cancer is the most common malignancy in women around the world. Intratumor and
intertumoral heterogeneity persist in mammary tumors. Therefore, the identification of …
intertumoral heterogeneity persist in mammary tumors. Therefore, the identification of …
The regulation of microRNAs on chemoresistance in triple-negative breast cancer: a recent update
LJ Yan, AT Y. Lau, YM Xu - Epigenomics, 2024 - Taylor & Francis
Triple-negative breast cancer (TNBC) has negative expressions of ER, PR and HER2. Due
to the insensitivity to both endocrine therapy and HER2-targeted therapy, the main treatment …
to the insensitivity to both endocrine therapy and HER2-targeted therapy, the main treatment …
The Tumor Suppressor Roles and Mechanisms of MiR-491 in Human Cancers
MicroRNAs (miRNAs) are short non-coding RNAs that bind to the 3′ untranslated region
(3′'UTR) of target mRNAs to control gene expression post-transcriptionally. Recent …
(3′'UTR) of target mRNAs to control gene expression post-transcriptionally. Recent …
[HTML][HTML] Deoxythymidylate kinase (DTYMK) participates in cell cycle arrest to promote pancreatic adenocarcinoma progression regulated by miR-491-5p through TP53 …
W Bao, H Yang, S Zhou, F Huang, Z Wei… - Journal of …, 2023 - ncbi.nlm.nih.gov
Background This study aimed to understand the mechanism of action of deoxythymidylate
kinase (DTYMK) and its effect on the prognosis of patients with pancreatic cancer. So as to …
kinase (DTYMK) and its effect on the prognosis of patients with pancreatic cancer. So as to …
Identification of Key Therapeutic Targets of Triptolide Against Breast Cancer by Integrated Transcriptomic Analysis and Co-expression Network Approach
L Yue, J Xing, W Chao, W Yingqiu, Z Lu, L Hongwei - 2024 - researchsquare.com
Background: Triptolide, a natural product extracted from Tripterygium wilfordii, has shown
anti-tumor activities against breast cancer (BC). This study aimed to identify potential …
anti-tumor activities against breast cancer (BC). This study aimed to identify potential …