Apoptosis is characterized by a series of dramatic perturbations to the cellular architecture
that contribute not only to cell death, but also prepare cells for removal by phagocytes and …

This review is directed at understanding how neuronal death occurs in two distinct insults,
global ischemia and focal ischemia. These are the two principal rodent models for human …

Apoptosis by Death Factor: Cell Skip to Main Content Advertisement Cell This journal offers
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The homeostasis of animals is regulated not only by the growth and differentiation of cells,
but also by cell death through a process known as apoptosis. Apoptosis is mediated by …

Lipid peroxidation is a well known example of oxidative damage in cell membranes,
lipoproteins, and other lipid-containing structures. Peroxidative modification of unsaturated …

Interleukin 1β-converting enzyme-like proteases (caspases) are crucial components of cell
death pathways. Among the caspases identified, caspase-3 stands out because it is …

Fas ligand (FasL), a cell surface molecule belonging to the tumor necrosis factor family,
binds to its receptor Fas, thus inducing apoptosis of Fas-bearing cells. Various cells express …

The concept of apoptotic cell death as an essential part of the development and life of
complex organisms has been devised in different situations and tested from various angles …

Mitochondrial cytochrome c (cyt c) has been found to have dual functions in controlling both
cellular energetic metabolism and apoptosis. Through interaction with apoptotic protease …

Programmed cell death (PCD) is a physiological process commonly defined by alterations in
nuclear morphology (apoptosis) and/or characteristic stepwise degradation of chromosomal …