The incretin effect, the amplification of insulin secretion occurring when glucose is taken in
orally as compared to infused intravenously, is one of the factors that help the body to …

Gut peptides, exemplified by glucagon-like peptide-1 (GLP-1) and glucose-dependent
insulinotropic polypeptide (GIP) are secreted in a nutrient-dependent manner and stimulate …

Paracrine interactions between pancreatic islet cells have been proposed as a mechanism
to regulate hormone secretion and glucose homeostasis. Here, we demonstrate the …

Incretins are gut hormones that are secreted from enteroendocrine cells into the blood within
minutes after eating. One of their many physiological roles is to regulate the amount of …

To elucidate the causes of the diminished incretin effect in type 2 diabetes mellitus we
investigated the secretion of the incretin hormones, glucagon-like peptide-1 and glucose …

Glucagon-Like Peptides | Endocrine Reviews | Oxford Academic Skip to Main Content
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Glucagon-like peptide 1 (GLP-1) is a hormone that is encoded in the proglucagon gene. It is
mainly produced in enteroendocrine L cells of the gut and is secreted into the blood stream …

The physiological effects of glucagon-like peptide-1 (GLP-1) are of immense interest
because of the potential clinical relevance of this peptide. Produced in intestinal L-cells …

The pituitary adenylate cyclase-activating polypeptide (PACAP)/glucagon superfamily
includes nine hormones in humans that are related by structure, distribution (especially the …

This review examines the role of cross-presentation in tolerance and immunity. We discuss
(a) the antigenic requirements for cross-presentation,(b) the phenotype of the antigen …