Although recent technical advances in thrombectomy have revolutionised acute stroke
treatment, prevalence of disability and death related to stroke remain high. Therefore …

Stroke continues to be one of the leading causes of mortality and morbidity worldwide.
Restoration of cerebral blood flow by recombinant plasminogen activator (rtPA) with or …

Dementia is a clinical syndrome that affects approximately 47 million people worldwide and
is characterized by progressive and irreversible decline of cognitive, behavioral and …

Conventional mammalian ischemic stroke models for drug screening are technically
challenging, laborious and time-consuming. In this study, using Ponatinib as an inducer, we …

Easily accessible biomarkers for Alzheimer's dementia (AD) are lacking and established
clinical markers are limited in applicability. Blood is a common biofluid for biomarker …

Cellular communication within the brain is imperative for maintaining homeostasis and
mounting effective responses to pathological triggers like hypoxia. However, a …

Ischemic stroke, a devastating disease associated with high mortality and disability
worldwide, has emerged as an urgent public health issue. A-kinase anchoring proteins …

The last two decades have witnessed a rapid decrease in mortality due to acute cerebral
ischemia that paradoxically has led to a rapid increase in the number of patients that survive …

Growth-associated protein 43 (GAP-43) plays a central role in the formation of presynaptic
terminals, synaptic plasticity, and axonal growth and regeneration. During development …

Purpose Urokinase receptor (uPAR) promotes extracellular matrix proteolysis, regulates
adhesion and cell migration, transduces intracellular signals through interactions with the …