Oncolytic viruses (OVs) are an emerging treatment option for many cancer types and have
recently been the focus of extensive research aiming to develop their therapeutic potential …

As a promising therapeutic strategy, oncolytic virotherapy has shown potent anticancer
efficacy in numerous pre-clinical and clinical trials. Oncolytic viruses have the capacity for …

Human adenoviruses are large (150 MDa) doubled-stranded DNA viruses that cause
respiratory infections. These viruses are particularly pathogenic in healthy and immune …

Chemoresistance has doubled the effort needed to reach an effective treatment for cancer.
Now, scientists should consider molecular pathways and mechanisms involved in …

In 2015, oncolytic virotherapy was approved for clinical use, and in 2017, recombinant
adeno-associated virus (AAV) delivery was also approved. However, systemic …

Simple Summary Glioblastoma (GBM) is the most common form of primary malignant brain
tumor with a devastatingly poor prognosis. Tumor heterogeneity (cellular, molecular and …

Lung cancer is one of the malignant tumors that seriously threaten human health worldwide,
while the covid-19 virus has become people's nightmare after the coronavirus pandemic …

Background Temozolomide (TMZ) chemotherapy is a current standard of care for
glioblastoma (GBM), however it has only extended overall survival by a few months …

Simple Summary Oncolytic virotherapy (OVT) is a promising approach in cancer
immunotherapy. Oncolytic viruses (OVs) could be applied in cancer immunotherapy without …

Virotherpay is emerging as a promising strategy against cancer, and three oncolytic viruses
(OVs) have gained approval in different countries for the treatment of several cancer types …