Endothelial cells (ECs) form the inner linings of blood vessels, and are directly exposed to
endogenous hazard signals and metabolites in the circulatory system. The senescence and …

Immunopsychiatric field has rapidly accumulated evidence demonstrating the involvement of
both innate and adaptive immune components in psychotic disorders such as …

Background: Approximately one in four stroke patients suffer from recurrent vascular events,
underlying the necessity to improve secondary stroke prevention strategies. Immune …

The phenomenon of accumulation of senescent adaptive immunity cells in the elderly is
attracting attention due to the increasing risk of global epidemics and aging of the global …

Cardiovascular disease is currently the largest cause of mortality and disability globally,
surpassing communicable diseases, and atherosclerosis is the main contributor to this …

Exacerbated expression of TLR4 protein (foremost pattern recognition receptor) during
obesity could trigger NF-κB/iNOS signaling through linker protein (MyD88), predisposed to …

Vascular diseases pose major health challenges, and understanding their underlying
molecular mechanisms is essential to advance therapeutic interventions. Cellular …

Ischemic stroke (IS) is a fatal neurological disease that occurs when the blood flow to the
brain is disrupted, leading to brain tissue damage and functional impairment. Cellular …

Aging is a major risk factor of atherosclerosis through different complex pathways including
replicative cellular senescence and age-related clonal hematopoiesis. In addition to aging …

Aging is associated with a decline in immune function, thereby causing an increased
susceptibility to various diseases. Herein, we review immune diseases associated with …