Ellagic acid a multi-target bioactive compound for drug discovery in CNS? A narrative review
It is well-known that the health properties attributed to several fruits, herbs, seeds and their
processed foods/beverages are due to an important group of natural polyphenols classified …
processed foods/beverages are due to an important group of natural polyphenols classified …
Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology
S Liu, M Fan, JX Xu, LJ Yang, CC Qi, QR Xia… - Journal of …, 2022 - Springer
Background Alzheimer's disease (AD) is a neurodegenerative disease characterized by a
progressive decline in cognitive ability. Exosomes derived from bone-marrow mesenchymal …
progressive decline in cognitive ability. Exosomes derived from bone-marrow mesenchymal …
Role of the cholinergic anti-inflammatory reflex in central nervous system diseases
IE Ramos-Martínez, MC Rodríguez, M Cerbón… - International Journal of …, 2021 - mdpi.com
In several central nervous system diseases, it has been reported that inflammation may be
related to the etiologic process, therefore, therapeutic strategies are being implemented to …
related to the etiologic process, therefore, therapeutic strategies are being implemented to …
Sex differences in depression and anxiety
Depression and anxiety disorders carry a tremendous worldwide burden and emerge as a
significant cause of disability among western societies. Both disorders are known to …
significant cause of disability among western societies. Both disorders are known to …
Forebrain cholinergic signaling regulates innate immune responses and inflammation
KR Lehner, HA Silverman, ME Addorisio… - Frontiers in …, 2019 - frontiersin.org
The brain regulates physiological functions integral to survival. However, the insight into
brain neuronal regulation of peripheral immune function and the neuromediator systems …
brain neuronal regulation of peripheral immune function and the neuromediator systems …
Neuroinflammation in Alzheimer's disease and beneficial action of luteolin
A Delgado, C Cholevas, TC Theoharides - Biofactors, 2021 - Wiley Online Library
Abstract Alzheimer's disease (AD), already the world's most common form of dementia, is
projected to continue increasing in prevalence over the next several decades. The current …
projected to continue increasing in prevalence over the next several decades. The current …
Acetylcholine regulates pulmonary pathology during viral infection and recovery
AP Horkowitz, AV Schwartz, CA Alvarez… - ImmunoTargets and …, 2020 - Taylor & Francis
Introduction This study was designed to explore the role of acetylcholine (ACh) in pulmonary
viral infection and recovery. Inflammatory control is critical to recovery from respiratory viral …
viral infection and recovery. Inflammatory control is critical to recovery from respiratory viral …
Alzheimer disease treatment with acetylcholinesterase inhibitors and incident age-related macular degeneration
SS Sutton, J Magagnoli, TH Cummings… - JAMA …, 2024 - jamanetwork.com
Importance Age-related macular degeneration (AMD) is a serious and common
ophthalmologic disorder that is hypothesized to result, in part, from inflammatory reactions in …
ophthalmologic disorder that is hypothesized to result, in part, from inflammatory reactions in …
Alterations in immune responses are associated with dysfunctional intracellular signaling in peripheral blood mononuclear cells of men and women with mild cognitive …
Deficits in the neuroendocrine-immune network in the periphery associated with the onset
and progression of mild cognitive impairment (MCI) and Alzheimer's disease (AD) have not …
and progression of mild cognitive impairment (MCI) and Alzheimer's disease (AD) have not …
Acetylcholinesterase inhibitors in Alzheimer's disease influence Zinc and Copper homeostasis
R Giacconi, C Giuli, T Casoli, M Balietti… - Journal of Trace …, 2019 - Elsevier
Background Alzheimer's disease (AD) is the most common age-related neurodegenerative
disease. An altered homeostasis of Zinc (Zn) and Copper (Cu), as well as a dysregulated …
disease. An altered homeostasis of Zinc (Zn) and Copper (Cu), as well as a dysregulated …