Inhaled medicines: past, present, and future
The purpose of this review is to summarize essential pharmacological, pharmaceutical, and
clinical aspects in the field of orally inhaled therapies that may help scientists seeking to …
clinical aspects in the field of orally inhaled therapies that may help scientists seeking to …
Lipid nanoparticles as delivery vehicles for inhaled therapeutics
EWX Leong, R Ge - Biomedicines, 2022 - mdpi.com
Lipid nanoparticles (LNPs) have emerged as a powerful non-viral carrier for drug delivery.
With the prevalence of respiratory diseases, particularly highlighted by the current COVID-19 …
With the prevalence of respiratory diseases, particularly highlighted by the current COVID-19 …
Inhaled nanoparticles–An updated review
T Praphawatvet, JI Peters, RO Williams III - International journal of …, 2020 - Elsevier
We are providing an update to our previously published review paper on inhaled
nanoparticles, thus updating with the most recent reports in the literature. The field of …
nanoparticles, thus updating with the most recent reports in the literature. The field of …
Group 3 pulmonary hypertension: from bench to bedside
N Singh, P Dorfmüller, OA Shlobin… - Circulation …, 2022 - Am Heart Assoc
Pulmonary hypertension (PH) because of chronic lung disease is categorized as Group 3
PH in the most recent classification system. Prevalence of these diseases is increasing over …
PH in the most recent classification system. Prevalence of these diseases is increasing over …
[HTML][HTML] Recent advances in prodrug-based nanoparticle therapeutics
KJ Chen, AJ Plaunt, FG Leifer, JY Kang… - European Journal of …, 2021 - Elsevier
Extensive research into prodrug modification of active pharmaceutical ingredients and
nanoparticle drug delivery systems has led to unprecedented levels of control over the …
nanoparticle drug delivery systems has led to unprecedented levels of control over the …
[HTML][HTML] Recent advances on nanoparticle-based therapies for cardiovascular diseases
RS Soumya, KG Raghu - Journal of Cardiology, 2023 - Elsevier
Nanoparticles are exclusively suitable for studying and developing potential therapies
against cardiovascular diseases (CVD) because of their size, fine-tunable properties, and …
against cardiovascular diseases (CVD) because of their size, fine-tunable properties, and …
[HTML][HTML] Macrophage-derived PDGF-B induces muscularization in murine and human pulmonary hypertension
Excess macrophages and smooth muscle cells (SMCs) characterize many cardiovascular
diseases, but crosstalk between these cell types is poorly defined. Pulmonary hypertension …
diseases, but crosstalk between these cell types is poorly defined. Pulmonary hypertension …
Polymerization-induced self-assembly generating vesicles with adjustable pH-responsive release performance
XF Xu, CY Pan, WJ Zhang, CY Hong - Macromolecules, 2019 - ACS Publications
Stimuli-responsive polymeric vesicles have attracted great attention in drug delivery due to
their intrinsic hollow structures and “on demand” release of drugs upon environmental …
their intrinsic hollow structures and “on demand” release of drugs upon environmental …
[HTML][HTML] Long-acting inhaled medicines: present and future
C Zhang, D D'Angelo, F Buttini, M Yang - Advanced Drug Delivery Reviews, 2023 - Elsevier
Inhaled medicines continue to be an essential part of treatment for respiratory diseases such
as asthma, chronic obstructive pulmonary disease, and cystic fibrosis. In addition, inhalation …
as asthma, chronic obstructive pulmonary disease, and cystic fibrosis. In addition, inhalation …
Nanomedicine-mediated therapeutic approaches for pulmonary arterial hypertension
E Mirhadi, P Kesharwani, TP Johnston… - Drug Discovery Today, 2023 - Elsevier
Highlights•Nanomedicine has emerged as a field with great opportunities to improve
treatment strategies.•Pulmonary arterial hypertension (PAH) is a serious and incurable …
treatment strategies.•Pulmonary arterial hypertension (PAH) is a serious and incurable …