Aluminum environmental pollution: the silent killer

RH Alasfar, RJ Isaifan - Environmental Science and Pollution Research, 2021 - Springer
The concern about aluminum (Al) toxicity has been proven in various cases. Some cases
are associated with the fact that Al is a neurotoxic substance that has been found in high …

Aggregated aluminium exposure: risk assessment for the general population

T Tietz, A Lenzner, AE Kolbaum, S Zellmer… - Archives of …, 2019 - Springer
Aluminium is one of the most abundant elements in earth's crust and its manifold uses result
in an exposure of the population from many sources. Developmental toxicity, effects on the …

Microglial activation in metal neurotoxicity: impact in neurodegenerative diseases

MI Martínez-Hernández… - BioMed Research …, 2023 - Wiley Online Library
Neurodegenerative processes encompass a large variety of diseases with different
pathological patterns and clinical features, such as Alzheimer's and Parkinson's diseases …

Clinical considerations in early-onset cerebral amyloid angiopathy

G Banerjee, J Collinge, NC Fox, T Lashley, S Mead… - Brain, 2023 - academic.oup.com
Cerebral amyloid angiopathy (CAA) is an important cerebral small vessel disease
associated with brain haemorrhage and cognitive change. The commonest form, sporadic …

Molecular mechanisms of aluminum neurotoxicity: Update on adverse effects and therapeutic strategies

AV Skalny, M Aschner, Y Jiang, YG Gluhcheva… - Advances in …, 2021 - Elsevier
Recent studies have demonstrated that brain may be considered as the target for aluminium
(Al) toxicity, resulting in development of neurodegenerative and neurodevelopmental …

Aluminum and amyloid-β in familial Alzheimer's disease

M Mold, C Linhart, J Gómez-Ramírez… - Journal of …, 2020 - content.iospress.com
Genetic predispositions associated with metabolism of the amyloid-β protein precursor
underlie familial Alzheimer's disease; a form of dementia characterized by early disease …

Aluminium in human brain tissue: how much is too much?

C Exley, MJ Mold - JBIC Journal of Biological Inorganic Chemistry, 2019 - Springer
A burgeoning body of research confirms and affirms the presence of aluminium in human
brain tissue. Recently, the first data on aluminium content of brain tissue from donors with …

Assessment of the Concentration of 51 Elements in the Liver and in Various Parts of the Human Brain—Profiling of the Mineral Status

J Baj, B Kowalska, W Flieger, E Radzikowska-Büchner… - Nutrients, 2023 - mdpi.com
The anthropogenic environment and diet introduce many metals into the human body, both
essential and toxic. Absorption leads to systemic exposure and accumulation in body fluids …

Aluminum and neurofibrillary tangle co-localization in familial Alzheimer's disease and related neurological disorders

MJ Mold, A O'Farrell, B Morris… - Journal of Alzheimer's …, 2020 - content.iospress.com
Background: Protein misfolding disorders are frequently implicated in neurodegenerative
conditions. Familial Alzheimer's disease (fAD) is an early-onset and aggressive form of …

Reviewing the association between aluminum adjuvants in the vaccines and autism spectrum disorder

A Boretti - Journal of Trace Elements in Medicine and Biology, 2021 - Elsevier
The manuscript reviews the association between aluminum adjuvants (AlAd) in vaccines
and autism spectrum disorder (ASD). Aluminum (Al) is neurotoxic. Infants who have received …