Objective To revise and expand the 1992 edition of the clinical practice guidelines for the
management of diabetes in Canada incorporating recent advances in diagnosis and …

Renal disease and hypertension in non–insulin-dependent diabetes mellitus. Recent
epidemiologic data demonstrate a dramatic increase in the incidence of end-stage renal …

People with type 1 and type 2 diabetes are at risk of developing progressive chronic kidney
disease (CKD) and end-stage kidney failure. Hypertension is a major, reversible risk factor …

OBJECTIVE—Conflicting evidence of a decline in incidence of microvascular complications
in type 1 diabetes during the last decades has been reported. To assess recent trends in the …

Background: Diabetic nephropathy is the leading cause of end-stage renal disease in
developed countries. Duration of diabetes, blood pressure values, and metabolic status are …

OBJECTIVE: The predictive value of microalbuminuria (MA) in children with type 1 diabetes
has not been defined. We describe the natural history of MA in a large cohort of children …

Some patients with essential hypertension manifest greater than normal urinary albumin
excretion (UAE). The significance of this association, which is the object of this review, is not …

The incidence of end-stage renal failure in patients with type II diabetes has dramatically
increased in recent years, both in the United States and, with some delay, in some European …

Nephrologists “rediscovered” smoking as a major renal risk factor in 1997 (1), although
investigators in the 19th and 20th centuries had noted an association between smoking and …

The adverse health effects of smoking are widely known. The health problems and costs
associated with smoking have recently been extensively reviewed [1—3]. Smoking-induced …