Global Cancer Statistics 2022: the trends projection analysis

BS Chhikara, K Parang - Chemical Biology Letters, 2023 - pubs.thesciencein.org
Cancer is one of the most fatal diseases of recent times that causes several deaths every
year. The disease variations in different parts of the world, the impact of available medical …

Trial watch: chemotherapy-induced immunogenic cell death in oncology

J Sprooten, RS Laureano, I Vanmeerbeek… - …, 2023 - Taylor & Francis
Immunogenic cell death (ICD) refers to an immunologically distinct process of regulated cell
death that activates, rather than suppresses, innate and adaptive immune responses. Such …

Anticancer drugs in wastewater and natural environments: A review on their occurrence, environmental persistence, treatment, and ecological risks

A Castellano-Hinojosa, MJ Gallardo-Altamirano… - Journal of Hazardous …, 2023 - Elsevier
The consumption of anticancer drugs (also known as chemotherapy drugs or antineoplastic
drugs) has augmented over the last decades due to increased cancer incidence. Although …

Lipid nanoparticles functionalized with antibodies for anticancer drug therapy

AC Marques, PC Costa, S Velho, MH Amaral - Pharmaceutics, 2023 - mdpi.com
Nanotechnology takes the lead in providing new therapeutic options for cancer patients. In
the last decades, lipid-based nanoparticles—solid lipid nanoparticles (SLNs) …

[HTML][HTML] Simulation-based approaches for drug delivery systems: navigating advancements, opportunities, and challenges

I Salahshoori, M Golriz, MAL Nobre, S Mahdavi… - Journal of Molecular …, 2023 - Elsevier
Efficient drug delivery systems (DDSs) play a pivotal role in ensuring pharmaceuticals'
targeted and effective administration. However, the intricate interplay between drug …

Codelivery of phytochemicals with conventional anticancer drugs in form of nanocarriers

G Kumar, T Virmani, A Sharma, K Pathak - Pharmaceutics, 2023 - mdpi.com
Anticancer drugs in monotherapy are ineffective to treat various kinds of cancer due to the
heterogeneous nature of cancer. Moreover, available anticancer drugs possessed various …

Recent drug design strategies and identification of key heterocyclic scaffolds for promising anticancer targets

A Mushtaq, P Wu, MM Naseer - Pharmacology & Therapeutics, 2023 - Elsevier
Cancer, a noncommunicable disease, is the leading cause of mortality worldwide and is
anticipated to rise by 75% in the next two decades, reaching approximately 25 million cases …

[HTML][HTML] Challenges and opportunities for improving the druggability of natural product: Why need drug delivery system?

P Tang, T Shen, H Wang, R Zhang, X Zhang… - Biomedicine & …, 2023 - Elsevier
Bioactive natural products (BNPs) are the marrow of medicinal plants, which are the
secondary metabolites of organisms and have been the most famous drug discovery …

Multi-targeting liposomal codelivery of cisplatin and rapamycin inhibits pancreatic cancer growth and metastasis through stromal modulation

W Zhu, H Yu, M Jia, C Lin, Z Yuan, X Tan… - International Journal of …, 2023 - Elsevier
Pancreatic cancer treatment faces challenges due to drug resistance as well as liver
metastasis. As a new strategy for treating pancreatic cancer, combination therapy is now …

Chitosan-based nano-smart drug delivery system in breast cancer therapy

Y Herdiana, N Wathoni, D Gozali, S Shamsuddin… - Pharmaceutics, 2023 - mdpi.com
Despite recent advances, cancer remains the primary killer on a global scale. Numerous
forms of research have been conducted to discover novel and efficient anticancer …