Exciting new advances in neuro‐oncology: the avenue to a cure for malignant glioma

EG Van Meir, CG Hadjipanayis… - CA: a cancer journal …, 2010 - Wiley Online Library
Malignant gliomas are the most common and deadly brain tumors. Nevertheless, survival for
patients with glioblastoma, the most aggressive glioma, although individually variable, has …

Primary brain tumours in adults

D Ricard, A Idbaih, F Ducray, M Lahutte… - The Lancet, 2012 - thelancet.com
Important advances have been made in the understanding and management of adult
gliomas and primary CNS lymphomas—the two most common primary brain tumours …

Combination therapy to checkmate Glioblastoma: clinical challenges and advances

D Ghosh, S Nandi, S Bhattacharjee - Clinical and translational medicine, 2018 - Springer
Combination therapy is increasingly becoming the cornerstone of current day antitumor
therapy. Glioblastoma multiforme is an aggressive brain tumor with a dismal median survival …

Glioblastoma, a brief review of history, molecular genetics, animal models and novel therapeutic strategies

S Agnihotri, KE Burrell, A Wolf, S Jalali… - Archivum immunologiae …, 2013 - Springer
Glioblastoma (GBM) is the most common and lethal primary brain tumor. Over the past few
years tremendous genomic and proteomic characterization along with robust animal models …

EGFRvIII antibody–conjugated iron oxide nanoparticles for magnetic resonance imaging–guided convection-enhanced delivery and targeted therapy of glioblastoma

CG Hadjipanayis, R Machaidze, M Kaluzova, L Wang… - Cancer research, 2010 - AACR
The magnetic nanoparticle has emerged as a potential multifunctional clinical tool that can
provide cancer cell detection by magnetic resonance imaging (MRI) contrast enhancement …

Ependymal cells: biology and pathology

MR Del Bigio - Acta neuropathologica, 2010 - Springer
The literature was reviewed to summarize the current understanding of the role of ciliated
ependymal cells in the mammalian brain. Previous reviews were summarized. Publications …

N-cadherin upregulation mediates adaptive radioresistance in glioblastoma

S Osuka, D Zhu, Z Zhang, C Li… - The Journal of …, 2021 - Am Soc Clin Investig
Glioblastoma (GBM) is composed of heterogeneous tumor cell populations, including those
with stem cell properties, termed glioma stem cells (GSCs). GSCs are innately less radiation …

[HTML][HTML] Tumor suppressive miRNA-34a suppresses cell proliferation and tumor growth of glioma stem cells by targeting Akt and Wnt signaling pathways

SS Rathod, SB Rani, M Khan, D Muzumdar, A Shiras - FEBS open bio, 2014 - Elsevier
MiRNA-34a is considered as a potential prognostic marker for glioma, as studies suggest
that its expression negatively correlates with patient survival in grade III and IV glial tumors …

Oncogenic effects of miR-10b in glioblastoma stem cells

F Guessous, M Alvarado-Velez, L Marcinkiewicz… - Journal of neuro …, 2013 - Springer
MicroRNAs and cancer stem cells have emerged as critical players in glioblastoma, one of
the deadliest human cancers. In this study, we investigated the expression and function of …

Magnetic nanoparticles: an emerging technology for malignant brain tumor imaging and therapy

M Wankhede, A Bouras, M Kaluzova… - Expert review of …, 2012 - Taylor & Francis
Magnetic nanoparticles (MNPs) represent a promising nanomaterial for the targeted therapy
and imaging of malignant brain tumors. Conjugation of peptides or antibodies to the surface …