Curcumin as an alternative epigenetic modulator: mechanism of action and potential effects

F Hassan, MS Rehman, MS Khan, MA Ali… - Frontiers in …, 2019 - frontiersin.org
Curcumin (a polyphenolic compound in turmeric) is famous for its potent anti-inflammatory,
anti-oxidant, and anti-cancer properties, and has a great potential to act as an epigenetic …

The animal trypanosomiases and their chemotherapy: a review

F Giordani, LJ Morrison, TG Rowan, HP De Koning… - Parasitology, 2016 - cambridge.org
Pathogenic animal trypanosomes affecting livestock have represented a major constraint to
agricultural development in Africa for centuries, and their negative economic impact is …

[图书][B] Amino acids: biochemistry and nutrition

G Wu - 2021 - taylorfrancis.com
Following its predecessor, the second edition of Amino Acids: Biochemistry and Nutrition
presents exhaustive coverage of amino acids in the nutrition, metabolism and health of …

Clinical features, diagnosis, and treatment of human African trypanosomiasis (sleeping sickness)

PGE Kennedy - The Lancet Neurology, 2013 - thelancet.com
Human African trypanosomiasis, or sleeping sickness, is caused by infection with parasites
of the genus Trypanosoma, transmitted by the tsetse fly. The disease has two forms …

Recent applications of vinyl sulfone motif in drug design and discovery

R Ahmadi, S Emami - European Journal of Medicinal Chemistry, 2022 - Elsevier
Vinyl sulfone with electrophilic character is not only a versatile building block for various
organic transformations but also is a key structural unit in a large number of biologically …

Loop-mediated isothermal amplification (LAMP): a rapid, accurate, and cost-effective diagnostic method for infectious diseases

Y Mori, T Notomi - Journal of infection and chemotherapy, 2009 - Elsevier
Loop-mediated isothermal amplification (LAMP) is an established nucleic acid amplification
method offering rapid, accurate, and cost-effective diagnosis of infectious diseases. This …

The Genome of the African Trypanosome Trypanosoma brucei

M Berriman, E Ghedin, C Hertz-Fowler, G Blandin… - science, 2005 - science.org
African trypanosomes cause human sleeping sickness and livestock trypanosomiasis in sub-
Saharan Africa. We present the sequence and analysis of the 11 megabase-sized …

Natively Inhibited Trypanosoma brucei Cathepsin B Structure Determined by Using an X-ray Laser

L Redecke, K Nass, DP DePonte, TA White, D Rehders… - Science, 2013 - science.org
The Trypanosoma brucei cysteine protease cathepsin B (TbCatB), which is involved in host
protein degradation, is a promising target to develop new treatments against sleeping …

Emerging and reemerging neglected tropical diseases: a review of key characteristics, risk factors, and the policy and innovation environment

TK Mackey, BA Liang, R Cuomo, R Hafen… - Clinical microbiology …, 2014 - Am Soc Microbiol
In global health, critical challenges have arisen from infectious diseases, including the
emergence and reemergence of old and new infectious diseases. Emergence and …

Cameroonian medicinal plants: pharmacology and derived natural products

V Kuete, T Efferth - Frontiers in pharmacology, 2010 - frontiersin.org
Many developing countries including Cameroon have mortality patterns that reflect high
levels of infectious diseases and the risk of death during pregnancy and childbirth, in …