Clinical neurology and epidemiology of the major neurodegenerative diseases
MG Erkkinen, MO Kim… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Neurodegenerative diseases are a common cause of morbidity and cognitive impairment in
older adults. Most clinicians who care for the elderly are not trained to diagnose these …
older adults. Most clinicians who care for the elderly are not trained to diagnose these …
The effects of aging in the hippocampus and cognitive decline
Aging is a natural process that is associated with cognitive decline as well as functional and
social impairments. One structure of particular interest when considering aging and …
social impairments. One structure of particular interest when considering aging and …
Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies
Dementia is increasingly being recognized in cases of Parkinson's disease (PD); such cases
are termed PD dementia (PDD). The spread of fibrillar α-synuclein (α-syn) pathology from …
are termed PD dementia (PDD). The spread of fibrillar α-synuclein (α-syn) pathology from …
Parkinson disease subtypes
MA Thenganatt, J Jankovic - JAMA neurology, 2014 - jamanetwork.com
Importance It is increasingly evident that Parkinson disease (PD) is not a single entity but
rather a heterogeneous neurodegenerative disorder. Objective To evaluate available …
rather a heterogeneous neurodegenerative disorder. Objective To evaluate available …
Cognitive impairment in patients with Parkinson's disease: diagnosis, biomarkers, and treatment
Dementia is one of the most common and important aspects of Parkinson's disease and has
consequences for patients and caregivers, and has health-related costs. Mild cognitive …
consequences for patients and caregivers, and has health-related costs. Mild cognitive …
Lewy body dementias
Z Walker, KL Possin, BF Boeve, D Aarsland - The Lancet, 2015 - thelancet.com
The broad importance of dementia is undisputed, with Alzheimer's disease justifiably getting
the most attention. However, dementia with Lewy bodies and Parkinson's disease dementia …
the most attention. However, dementia with Lewy bodies and Parkinson's disease dementia …
In vivo cholinergic basal forebrain atrophy predicts cognitive decline in de novo Parkinson's disease
Abstract See Gratwicke and Foltynie (doi: 10.1093/brain/awx333) for a scientific commentary
on this article. Cognitive impairments are a prevalent and disabling non-motor complication …
on this article. Cognitive impairments are a prevalent and disabling non-motor complication …
The neuropsychiatry of Parkinson disease: a perfect storm
D Weintraub, E Mamikonyan - The American Journal of Geriatric Psychiatry, 2019 - Elsevier
Affective disorders, cognitive decline, and psychosis have long been recognized as common
in Parkinson disease (PD), and other psychiatric disorders include impulse control …
in Parkinson disease (PD), and other psychiatric disorders include impulse control …
Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease
WT Hu, DM Holtzman, AM Fagan, LM Shaw, R Perrin… - Neurology, 2012 - AAN Enterprises
Objectives: While plasma biomarkers have been proposed to aid in the clinical diagnosis of
Alzheimer disease (AD), few biomarkers have been validated in independent patient …
Alzheimer disease (AD), few biomarkers have been validated in independent patient …
Biomarkers for dementia and mild cognitive impairment in Parkinson's disease
M Delgado‐Alvarado, B Gago… - Movement …, 2016 - Wiley Online Library
Cognitive decline is one of the most frequent and disabling nonmotor features of Parkinson's
disease. Around 30% of patients with Parkinson's disease experience mild cognitive …
disease. Around 30% of patients with Parkinson's disease experience mild cognitive …