MRI of the lungs using hyperpolarized noble gases
HE Möller, XJ Chen, B Saam… - … in Medicine: An …, 2002 - Wiley Online Library
The nuclear spin polarization of the noble gas isotopes 3He and 129Xe can be increased
using optical pumping methods by four to five orders of magnitude. This extraordinary gain …
using optical pumping methods by four to five orders of magnitude. This extraordinary gain …
Neutrophils, interleukin-17A and lung disease
A Linden, M Laan, GP Anderson - European Respiratory …, 2005 - Eur Respiratory Soc
It is now established that an excessive and sustained mobilisation of neutrophils is a
hallmark of several chronic inflammatory lung disorders, including severe obstructive lung …
hallmark of several chronic inflammatory lung disorders, including severe obstructive lung …
[HTML][HTML] An official research policy statement of the American Thoracic Society/European Respiratory Society: standards for quantitative assessment of lung structure
The charge of this Joint ATS/ERS Task Force was to critically review the state-of-the-art
stereological methods in lung morphometry, provide practical guidelines for use of these …
stereological methods in lung morphometry, provide practical guidelines for use of these …
Optimized 3D ultrashort echo time pulmonary MRI
Purpose To optimize 3D radial ultrashort echo time MRI for high resolution whole‐lung
imaging. Methods 3D radial ultrashort echo time was implemented on a 3T scanner to …
imaging. Methods 3D radial ultrashort echo time was implemented on a 3T scanner to …
Alveolarization continues during childhood and adolescence: new evidence from helium-3 magnetic resonance
M Narayanan, J Owers-Bradley… - American journal of …, 2012 - atsjournals.org
Rationale: The current hypothesis that human pulmonary alveolarization is complete by 3
years is contradicted by new evidence of alveolarization throughout adolescence in …
years is contradicted by new evidence of alveolarization throughout adolescence in …
Quantitative in vivo assessment of lung microstructure at the alveolar level with hyperpolarized 3He diffusion MRI
DA Yablonskiy, AL Sukstanskii… - Proceedings of the …, 2002 - National Acad Sciences
The study of lung emphysema dates back to the beginning of the 17th century. Nevertheless,
a number of important questions remain unanswered because a quantitative localized …
a number of important questions remain unanswered because a quantitative localized …
Diffusion‐weighted hyperpolarized 129Xe MRI in healthy volunteers and subjects with chronic obstructive pulmonary disease
SS Kaushik, ZI Cleveland, GP Cofer… - Magnetic …, 2011 - Wiley Online Library
Given its greater availability and lower cost, 129Xe apparent diffusion coefficient (ADC) MRI
offers an alternative to 3He ADC MRI. To demonstrate the feasibility of hyperpolarized …
offers an alternative to 3He ADC MRI. To demonstrate the feasibility of hyperpolarized …
Imaging alveolar–capillary gas transfer using hyperpolarized 129Xe MRI
B Driehuys, GP Cofer, J Pollaro… - Proceedings of the …, 2006 - National Acad Sciences
Effective pulmonary gas exchange relies on the free diffusion of gases across the thin tissue
barrier separating airspace from the capillary red blood cells (RBCs). Pulmonary …
barrier separating airspace from the capillary red blood cells (RBCs). Pulmonary …
Functional imaging of the lungs with gas agents
This review focuses on the state‐of‐the‐art of the three major classes of gas contrast agents
used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen …
used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen …
Catch-up Alveolarization in Ex-Preterm Children. Evidence from 3He Magnetic Resonance
M Narayanan, CS Beardsmore… - American journal of …, 2013 - atsjournals.org
Rationale: Histologic data from fatal cases suggest that extreme prematurity results in
persisting alveolar damage. However, there is new evidence that human alveolarization …
persisting alveolar damage. However, there is new evidence that human alveolarization …