Towards developing biomarkers for glioblastoma multiforme: a proteomics view

S Jayaram, MK Gupta, RV Polisetty… - Expert review of …, 2014 - Taylor & Francis
Glioblastoma multiforme (GBM) is one of the most aggressive and lethal forms of the primary
brain tumors. With predominance of tumor heterogeneity and emergence of new subtypes …

Glioma tumor proteomics: clinically useful protein biomarkers and future perspectives

S Ghantasala, K Gollapalli, S Epari… - Expert Review of …, 2020 - Taylor & Francis
Introduction: Despite being rare cancers, gliomas account for a significant number of cancer-
related deaths. Identification and treatment of these tumors at an early stage would greatly …

[HTML][HTML] Altered transcriptional regulatory proteins in glioblastoma and YBX1 as a potential regulator of tumor invasion

MK Gupta, RV Polisetty, R Sharma, RA Ganesh… - Scientific reports, 2019 - nature.com
We have studied differentially regulated nuclear proteome of the clinical tissue specimens of
glioblastoma (GBM, WHO Grade IV) and lower grades of gliomas (Grade II and III) using …

Evaluation of non-supervised MALDI mass spectrometry imaging combined with microproteomics for glioma grade III classification

E Le Rhun, M Duhamel, M Wisztorski… - … et Biophysica Acta (BBA …, 2017 - Elsevier
An integrated diagnosis using molecular features is recommended in the 2016 World Health
Organization (WHO) classification. Our aim was to explore non-targeted molecular …

[HTML][HTML] Quantitative proteomic analysis of GnRH agonist treated GBM cell line LN229 revealed regulatory proteins inhibiting cancer cell proliferation

PH Tripathi, J Akhtar, J Arora, RK Saran, N Mishra… - BMC cancer, 2022 - Springer
Abstract Background Gonadotropin-releasing hormone (GnRH) receptor, a rhodopsin-like G-
protein coupled receptor (GPCR) family member involved in GnRH signaling, is reported to …

iTRAQ Protein Profile Analysis of Tomato Green-ripe Mutant Reveals New Aspects Critical for Fruit Ripening

X Pan, B Zhu, H Zhu, Y Chen, H Tian… - Journal of Proteome …, 2014 - ACS Publications
Green-ripe (Gr) tomato carries a dominant mutation and yields a nonripening fruit
phenotype. The mutation results from a 334 bp deletion in a gene of unknown function at the …

Chromosome-centric human proteome project: deciphering proteins associated with glioma and neurodegenerative disorders on chromosome 12

MK Gupta, S Jayaram, AK Madugundu… - Journal of Proteome …, 2014 - ACS Publications
In line with the aims of the Chromosome-centric Human Proteome Project (C-HPP) to
completely annotate proteins of each chromosome and biology/disease driven HPP (B/D …

Differential proteomics analysis of low-and high-grade of astrocytoma using iTRAQ quantification

T Ren, S Lin, Z Wang, A Shang - OncoTargets and therapy, 2016 - Taylor & Francis
Astrocytoma is one of the most common types of brain tumor, which is histologically and
clinically classified into four grades (I–IV): I (pilocytic astrocytoma), II (diffuse astrocytoma), III …

[HTML][HTML] Microsomal membrane proteome of low grade diffuse astrocytomas: Differentially expressed proteins and candidate surveillance biomarkers

RV Polisetty, P Gautam, MK Gupta, R Sharma… - Scientific reports, 2016 - nature.com
Diffuse astrocytoma (DA; WHO grade II) is a low-grade, primary brain neoplasm with high
potential of recurrence as higher grade malignant form. We have analyzed differentially …

ITRAQ-based proteomic analysis of apple buds provides new insights into regulatory mechanisms of flowering in response to shoot bending

S Liu, T Shi, D Zhang, X Zhang, T Fan, P Mu, H Yue… - Scientia …, 2021 - Elsevier
Flowering is an important life cycle stage in apple trees, and young 'Nagafu No. 2'produce
limited inferior flower buds. Shoot bending, an effective agronomic measure, is widely used …