This article sheds light on the various scaffolds that can be used in the designing and
development of novel synthetic compounds to create DPP-4 inhibitors for the treatment of …

The purpose of this review is to summarize drugs containing an azoloazine moiety and
exhibiting antidiabetic activity. The review includes azoloazines active against dipeptidyl …

Nowadays, dipeptidyl peptidase-IV (DPP-IV) is emerging as a hopeful drug target for treating
Type 2 diabetic mellitus (T2DM). Currently marketed DPP-IV inhibitors work by lowering the …

This work presented the first report on designing, synthesizing of novel pyrazole-triazole-
persulfonimide (7a-i) and pyrazole-triazole-aryl derivatives (8a-j) via click reaction using CuI …

Xanthine is the most ubiquitous heterocyclic aromatic compound and have attracted much
synthetic interest due to their numerous pharmacological activities. It is one of the principal …

A one-pot procedure for the synthesis of novel 1, 2, 3-triazole derivatives (5a–5l) in good
yields (63 to 77%) using different sulfonic acids and 4-(prop-2-yn-1-yl) thiomorpholine 1, 1 …

Xanthine and its derivatives are considered a pharmacologically potential moiety that
manifests immense biological activities. Owing to this much diversity in the biological field …

Recent research on dipeptidyl peptidase-IV (DPP-IV) inhibitors has made it feasible to treat
type 2 diabetes mellitus (T2DM) with minimal side effects. Therefore, in the present …

Diabetes is a chronic, and metabolic disorder that has gained epidemic proportions in the
past few decades creating a threat throughout the globe. It is characterized by increased …

Diabetes mellitus (DM) is one of the largest public health problems worldwide and in the last
decades various therapeutic targetshave been investigated. For the treatment of type-2 DM …