Purpose: The International Myopia Institute (IMI) Yearly Digest highlights new research
considered to be of importance since the publication of the first series of IMI white papers …

Macromolecules comprise only 2% of vitreous, yet are responsible for its gel state,
transparency, and physiologic function (s) within the eye. Myopia and aging alter collagen …

Purpose Myopic vitreopathy features precocious fibrous vitreous liquefaction and early
posterior vitreous detachment (PVD). It is unclear whether visual function is affected by …

Purpose This study aims to investigate the potential bidirectional causal relationship
between myopia and vitreous disorders from a genetic perspective, as vitreous disorders …

Purpose: The purpose of this study was to evaluate the role of the canonical Wnt signaling in
the development of the myopia. Methods: Plasma from adult patients with myopia, myopic …

Purpose: Avoidable severe visual sequelae are prevalent among highly myopic eyes. We
analyzed the postoperative incidence of myopic traction maculopathy (MTM) progression …

Background: Pathological myopia, a severe variant of myopia, extends beyond the typical
refractive error associated with nearsightedness. While the condition has a strong genetic …

Background Many reports have shown that Wnt/β-Catenin pathway is associated with a
variety of diseases, but its role in the pathogenesis of myopia is still unknown. In order to …

Purpose: To compare quantitative changes in macular perfusion in normal eyes, healthy
highly myopic eyes, non-operated eyes with Myopic Foveoschisis (MF)/Foveoretinal …

Background: Pathological myopia can be complicated by the presence of posterior
staphyloma, macular atrophy, ruptures in Bruch's membrane, pathologic choroidal …