Overview of the cornea: structure, function, and development

AO Eghrari, SA Riazuddin, JD Gottsch - Progress in molecular biology and …, 2015 - Elsevier
The cornea is a transparent tissue with significant refractive and barrier functions. The
epithelium serves as the principal barrier to fluid and pathogens, a function performed …

The corneal fibrosis response to epithelial–stromal injury

AAM Torricelli, A Santhanam, J Wu, V Singh… - Experimental eye …, 2016 - Elsevier
The corneal wound healing response, including the development of stromal opacity in some
eyes, is a process that often leads to scarring that occurs after injury, surgery or infection to …

[HTML][HTML] A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells

J Collin, R Queen, D Zerti, S Bojic, B Dorgau, N Moyse… - The ocular …, 2021 - Elsevier
Purpose Single cell (sc) analyses of key embryonic, fetal and adult stages were performed to
generate a comprehensive single cell atlas of all the corneal and adjacent conjunctival cell …

Proteoglycans: from structural compounds to signaling molecules

L Schaefer, RM Schaefer - Cell and tissue research, 2010 - Springer
Our knowledge of proteoglycan biology has significantly expanded over the past decade
with the discovery of a host of new members of this multifunctional family leading to their …

Corneal biomechanics–a review

S Kling, F Hafezi - Ophthalmic and Physiological Optics, 2017 - Wiley Online Library
Purpose In recent years, the interest in corneal biomechanics has strongly increased. The
material properties of the cornea determine its shape and therefore play an important role in …

Wound healing in the cornea: a review of refractive surgery complications and new prospects for therapy

MV Netto, RR Mohan, R Ambrósio Jr, AEK Hutcheon… - Cornea, 2005 - journals.lww.com
Purpose: The corneal wound healing response is of particular relevance for refractive
surgical procedures since it is a major determinant of efficacy and safety. The purpose of this …

Concise review: stem cells in the corneal stroma

N Pinnamaneni, JL Funderburgh - Stem cells, 2012 - academic.oup.com
The cornea is a tough transparent tissue admitting and focusing light in the eye. More than
90% of the cornea is stroma, a highly organized, transparent connective tissue maintained …

Stereolithography 3D bioprinting method for fabrication of human corneal stroma equivalent

SS Mahdavi, MJ Abdekhodaie, H Kumar… - Annals of Biomedical …, 2020 - Springer
Abstract 3D bioprinting technology is a promising approach for corneal stromal tissue
regeneration. In this study, gelatin methacrylate (GelMA) mixed with corneal stromal cells …

Congenital anterior segment ocular disorders: Genotype-phenotype correlations and emerging novel mechanisms

LM Reis, S Seese, D Costakos, EV Semina - Progress in Retinal and Eye …, 2024 - Elsevier
Development of the anterior segment of the eye requires reciprocal sequential interactions
between the arising tissues, facilitated by numerous genetic factors. Disruption of any of …

How the cornea heals: cornea-specific repair mechanisms affecting surgical outcomes

ME Fini, BM Stramer - Cornea, 2005 - journals.lww.com
In mammals, penetrating injuries typically heal by deposition of fibrotic “repair tissue” that
fills and seals wounds but does not restore normal function. Excessive deposition of fibrotic …