HIV-1–host interaction in gut-associated lymphoid tissue (GALT): effects on local environment and comorbidities
S Moretti, I Schietroma, G Sberna… - International Journal of …, 2023 - mdpi.com
HIV-1 replication in the gastrointestinal (GI) tract causes severe CD4+ T-cell depletion and
disruption of the protective epithelial barrier in the intestinal mucosa, causing microbial …
disruption of the protective epithelial barrier in the intestinal mucosa, causing microbial …
Differential effects of antiretroviral treatment on immunity and gut microbiome composition in people living with HIV in rural versus urban Zimbabwe
AS Burkhart Colorado, A Lazzaro, CP Neff… - Microbiome, 2024 - Springer
Background The widespread availability of antiretroviral therapy (ART) has dramatically
reduced mortality and improved life expectancy for people living with HIV (PLWH). However …
reduced mortality and improved life expectancy for people living with HIV (PLWH). However …
Tissue‐specific differences in HIV DNA levels and mechanisms that govern HIV transcription in blood, gut, genital tract and liver in ART‐treated women
Introduction: Sex-specific differences affect multiple aspects of HIV infection, yet few studies
have quantified HIV levels in tissues from women. Since an HIV functional cure will likely …
have quantified HIV levels in tissues from women. Since an HIV functional cure will likely …
Common and Divergent Features of T Cells from Blood, Gut, and Genital Tract of Antiretroviral Therapy–Treated HIV+ Women
T cells residing in mucosal tissues play important roles in homeostasis and defense against
microbial pathogens. The gut and female reproductive tract (FRT) are both tolerogenic …
microbial pathogens. The gut and female reproductive tract (FRT) are both tolerogenic …
[HTML][HTML] Antiretroviral treatment is less effective at reducing gut microbiome-associated inflammation and T cell activation in people living with HIV in rural versus urban …
A Lazzaro, ASB Colorado, CP Neff, N Nusbacher… - Research …, 2023 - ncbi.nlm.nih.gov
The widespread availability of antiretroviral therapy (ART) for people living with HIV (PLWH)
has dramatically reduced mortality and improved life expectancy. However, even with …
has dramatically reduced mortality and improved life expectancy. However, even with …