The primary bile acids (BAs) are synthetized from cholesterol in the liver, conjugated to
glycine or taurine to increase their solubility, secreted into bile, concentrated in the …

The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing worldwide and
parallels comorbidities such as obesity, metabolic syndrome, dyslipidemia, and diabetes …

An update on the pathogenesis of cholesterol gallstone disea... : Current Opinion in
Gastroenterology An update on the pathogenesis of cholesterol gallstone disease : Current …

Tuft cells—rare solitary chemosensory cells in mucosal epithelia—are undergoing intense
scientific scrutiny fueled by recent discovery of unsuspected connections to type 2 immunity …

Although low doses of persistent organic pollutants (POPs), strong lipophilic chemicals with
long half‐lives, have been linked to various endocrine, immune, nervous and reproductive …

The high prevalence of cholesterol gallstones, the availability of new information about
pathogenesis, and the relevant health costs due to the management of cholelithiasis in both …

Abstract The Free Drug Hypothesis is a well-established concept within the scientific lexicon
pervading many areas of Drug Discovery and Development, and yet it is poorly defined by …

The gallbladder stores bile between meals and empties into the duodenum upon demand
and is thereby exposed to the intestinal microbiome. This exposure raises the need for …

Bile reflux gastritis (BRG), a kind of gastrointestinal disorder in clinical practice, is
characterized by regurgitation and inflammation. However, lack of guidelines leads to simple …

The size of the liver of terrestrial mammals obeys the allometric scaling law over a weight
range of> 3∗ 10 6. Since scaling reflects adaptive changes in size or scale among otherwise …