The schizophrenia syndrome, circa 2024: What we know and how that informs its nature

R Tandon, H Nasrallah, S Akbarian… - Schizophrenia …, 2024 - Elsevier
With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …

Functional neuroimaging in psychiatry and the case for failing better

MM Nour, Y Liu, RJ Dolan - Neuron, 2022 - cell.com
Psychiatric disorders encompass complex aberrations of cognition and affect and are
among the most debilitating and poorly understood of any medical condition. Current …

Immunoneuropsychiatry—novel perspectives on brain disorders

K Pape, R Tamouza, M Leboyer, F Zipp - Nature Reviews Neurology, 2019 - nature.com
Immune processes have a vital role in CNS homeostasis, resilience and brain reserve. Our
cognitive and social abilities rely on a highly sensitive and fine-tuned equilibrium of immune …

Validity and utility of hierarchical taxonomy of psychopathology (HiTOP): I. Psychosis superspectrum

R Kotov, KG Jonas, WT Carpenter, MN Dretsch… - World …, 2020 - Wiley Online Library
The Hierarchical Taxonomy of Psychopathology (HiTOP) is a scientific effort to address
shortcomings of traditional mental disorder diagnoses, which suffer from arbitrary …

Common dysfunction of large-scale neurocognitive networks across psychiatric disorders

Z Sha, TD Wager, A Mechelli, Y He - Biological psychiatry, 2019 - Elsevier
Background Cognitive dysfunction is one of the most prominent characteristics of psychiatric
disorders. Currently, the neural correlates of cognitive dysfunction across psychiatric …

Dopaminergic dysfunction and excitatory/inhibitory imbalance in treatment-resistant schizophrenia and novel neuromodulatory treatment

M Wada, Y Noda, Y Iwata, S Tsugawa, K Yoshida… - Molecular …, 2022 - nature.com
Antipsychotic drugs are the mainstay in the treatment of schizophrenia. However, one-third
of patients do not show adequate improvement in positive symptoms with non-clozapine …

General functional connectivity: Shared features of resting-state and task fMRI drive reliable and heritable individual differences in functional brain networks

ML Elliott, AR Knodt, M Cooke, MJ Kim, TR Melzer… - NeuroImage, 2019 - Elsevier
Intrinsic connectivity, measured using resting-state fMRI, has emerged as a fundamental tool
in the study of the human brain. However, due to practical limitations, many studies do not …

[HTML][HTML] What have we really learned from functional connectivity in clinical populations?

J Zhang, A Kucyi, J Raya, AN Nielsen, JS Nomi… - NeuroImage, 2021 - Elsevier
Functional connectivity (FC), or the statistical interdependence of blood-oxygen dependent
level (BOLD) signals between brain regions using fMRI, has emerged as a widely used tool …

Dysconnectivity of multiple brain networks in schizophrenia: a meta-analysis of resting-state functional connectivity

S Li, N Hu, W Zhang, B Tao, J Dai, Y Gong… - Frontiers in …, 2019 - frontiersin.org
Background: Seed-based studies on resting-state functional connectivity (rsFC) in
schizophrenia have shown disrupted connectivity involving a number of brain networks; …

Reducing the cognitive footprint of brain tumor surgery

NB Dadario, B Brahimaj, J Yeung… - Frontiers in neurology, 2021 - frontiersin.org
The surgical management of brain tumors is based on the principle that the extent of
resection improves patient outcomes. Traditionally, neurosurgeons have considered that …