Palladium/norbornene cooperative catalysis has emerged as a distinct approach to
construct polyfunctionalized arenes from readily available starting materials. This Review …

The last decades have seen a tremendous expanse in the application of C H activation of
many different substrate classes, including the invaluable indole scaffold. Following the …

Transition metal-catalyzed cross-coupling reactions of alkyl metals and aryl halides or
pseudohalides have emerged as a powerful methodology for the formation of Csp3-Csp2 …

The abundance of the biaryl structural motif in natural products, in biologically active
molecules and in materials chemistry has positioned aryl–aryl (Ar–Ar) bond formation high …

Conditions for the palladium-catalyzed direct arylation of a wide range of heterocycles with
aryl bromides are reported. Those conditions employ a stoichiometric ratio of both coupling …

(Hetero) aryl groups directly connected by single Csp2–Csp2 bonds to heteroaryl moieties
are present as core structures in many biologically active compounds, 1 naturally-occurring …

Through the introduction of an aryl chloride substituent, the selectivity of palladium-catalyzed
direct arylation may be diverted to provide alternative regioisomeric products in high yields …

In the late 1990s Catellani reported a remarkable palladium-catalyzed domino reaction [1] in
the presence of norbornene, in which aryl iodides were alkylated at the ortho positions by …

The intramolecular gold-catalyzed arylation of arenes by aryl-trimethylsilanes has been
investigated from both mechanistic and preparative aspects. The reaction generates 5-to 9 …

The bromodomain and extra-terminal domain (BET) family of proteins bind acetylated lysine
residues on histone proteins. The four BET bromodomains—BRD2, BRD3, BRD4, and …