Inhibin at 90: from discovery to clinical application, a historical review

Y Makanji, J Zhu, R Mishra, C Holmquist… - Endocrine …, 2014 - academic.oup.com
When it was initially discovered in 1923, inhibin was characterized as a hypophysiotropic
hormone that acts on pituitary cells to regulate pituitary hormone secretion. Ninety years …

Potential local regulatory functions of inhibins, activins and follistatin in the ovary

PG Knight, C Glister - Reproduction, 2001 - rep.bioscientifica.com
The changing pattern of granulosa cell expression of inhibin/activin subunits and follistatin
during follicle development and their differential regulation by extrinsic and intraovarian …

[HTML][HTML] Human infertility: are endocrine disruptors to blame?

A Marques-Pinto, D Carvalho - Endocrine connections, 2013 - ec.bioscientifica.com
Over recent decades, epidemiological studies have been reporting worrisome trends in the
incidence of human infertility rates. Extensive detection of industrial chemicals in human …

Estrogen receptor 1 (ESR1; ERα), not ESR2 (ERβ), modulates estrogen-induced sex reversal in the American alligator, a species with temperature-dependent sex …

S Kohno, MC Bernhard, Y Katsu, J Zhu, TA Bryan… - …, 2015 - academic.oup.com
All crocodilians and many turtles exhibit temperature-dependent sex determination where
the temperature of the incubated egg, during a thermo-sensitive period (TSP), determines …

[HTML][HTML] Application of quantitative transcriptomics in evaluating the ex vivo effects of per-and polyfluoroalkyl substances on Atlantic cod (Gadus morhua) ovarian …

EA Khan, X Zhang, EM Hanna, F Yadetie… - Science of the Total …, 2021 - Elsevier
Because of their global consumption and persistence, per-and polyfluoroalkyl substances
(PFASs), are ubiquitously distributed in the environment, as well as in wildlife and humans …

High contaminant loads in Lake Apopka's riparian wetland disrupt gene networks involved in reproduction and immune function in largemouth bass

CJ Martyniuk, NJ Doperalski, MS Prucha… - … and Physiology Part D …, 2016 - Elsevier
Abstract Lake Apopka (FL, USA) has elevated levels of some organochlorine pesticides in
its sediments and a portion of its watershed has been designated a US Environmental …

Endocrine disruption and in vitro ecotoxicology: recent advances and approaches

M Wagner, C Kienle, ELM Vermeirssen… - In vitro Environmental …, 2017 - Springer
Endocrine-disrupting chemicals (EDCs) are man-made compounds interfering with hormone
signaling. Omnipresent in the environment, they can cause adverse effects in a wide range …

[PDF][PDF] Influence of tissue, age, and environmental quality on DNA methylation in Alligator mississippiensis

BB Parrott, JA Bowden, S Kohno, JA Cloy-McCoy… - Reproduction, 2014 - tsapps.nist.gov
Epigenetic modifications are key mediators of the interactions between the environment and
an organism's genome. DNA methylation represents the best-studied epigenetic …

Environmentally relevant concentrations of nitrate increase plasma testosterone concentrations in female American alligators (Alligator mississippiensis)

HJ Hamlin, TM Edwards, J McCoy, L Cruze… - General and …, 2016 - Elsevier
Anthropogenic nitrogen is a ubiquitous environmental contaminant that is contributing to the
degradation of freshwater, estuarine, and coastal ecosystems worldwide. The effects of …

Transcriptional networks underlying a primary ovarian insufficiency disorder in alligators naturally exposed to EDCs

MD Hale, T Koal, TH Pham, JA Bowden… - Molecular and Cellular …, 2022 - Elsevier
Interactions between the endocrine system and environmental contaminants are
responsible for impairing reproductive development and function. Despite the taxonomic …