Highlights•We now have metabolic network models; the metabolome is represented by their
nodes.•Metabolite levels are sensitive to changes in enzyme activities.•Drugs hitchhike on …

Metabolomics is the latest of the ěomicî technologies that involves comprehensive analysis
of small molecule metabolites of an organism or a specific biological sample. Metabolomics …

AIM: To evaluate the utility of serum and urine metabolomic analysis in diagnosing and
monitoring of inflammatory bowel diseases (IBD). METHODS: Serum and urine samples …

Background The aetiology of inflammatory bowel disease (IBD) remains poorly understood.
Recent evidence suggests an important role of gut microbial dysbiosis in IBD, and this may …

Detection of metabolic disturbances in lung cancer (LC) has the potential to aid early
diagnosis/prognosis and hence improve disease management strategies through reliable …

Metabolome analysis is used to evaluate the characteristics and interactions of low
molecular weight metabolites under a specific set of conditions. In cirrhosis, hepatocellular …

Background Metabolomics is a versatile unbiased method to search for biomarkers of
human disease. In particular, one approach in cancer therapy is to promote apoptosis in …

Fanconi anemia (FA) is a rare inherited recessive disease caused by mutations in one of
fifteen genes known to encode FA pathway components. In response to DNA damage …

Background Many novel diagnostic biomarkers have been developed for gastric cancer
(GC) recently. We chose two methods with high diagnostic value, the detection of serum …

The metabolic profiles of breast cancer cells are different from normal mammary epithelial
cells. Breast cancer cells that gain resistance to therapeutic interventions can reprogram …